Global Patent Index - EP 1084118 A1

EP 1084118 A1 2001-03-21 - REDUCED PARTICLE SIZE FORM OF 1-(6-CHLORONAPHTH-2- YLSULPHONYL) -4- 4-(4PYRIDYL) BENZOYL PIPERAZINE

Title (en)

REDUCED PARTICLE SIZE FORM OF 1-(6-CHLORONAPHTH-2- YLSULPHONYL) -4- 4-(4PYRIDYL) BENZOYL PIPERAZINE

Title (de)

1-(6-CHLORNAPHTH-2-YLSULFONYL)-4-¬4-(4-PYRIDYL)BENZOYL PIPERAZIN MIT VERRINGERTER TEILCHENGRÖSSE

Title (fr)

FORME A GRANULOMETRIE REDUITE DE 1-(6-CHLORONAPHT-2- YLSULFONYL) -4- 4-(4-PYRIDYL) BENZOYL PIPERAZINE

Publication

EP 1084118 A1 (EN)

Application

EP 99919395 A

Priority

  • GB 9901316 W
  • GB 9809350 A

Abstract (en)

[origin: WO9957112A1] The invention relates to pharmaceutically acceptable salts of 1-(6-chloronaphth-2-ylsulphonyl)-4-[4-(4-pyridyl)benzoyl]piperazine and reduced particle size forms of either the compound or a pharmaceutically acceptable salt thereof, which possess antithrombotic and anticoagulant properties and accordingly are useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of pharmaceutically-acceptable salts of the above compound and reduced particle size forms thereof, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect in humans.

IPC 1-7 (main, further and additional classification)

C07D 401/10; A61K 31/495

IPC 8 full level (invention and additional information)

C07D 213/56 (2006.01); A61K 31/496 (2006.01); A61P 7/02 (2006.01); A61P 43/00 (2006.01); C07D 213/54 (2006.01)

CPC (invention and additional information)

C07D 213/54 (2013.01)

Citation (search report)

See references of WO 9957112A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

Designated extension state (EPC)

AL LT LV MK RO SI

EPO simple patent family

WO 9957112 A1 19991111; AU 3719699 A 19991123; BR 9910176 A 20010109; CA 2331041 A1 19991111; CN 1308629 A 20010815; EE 200000638 A 20020415; EP 1084118 A1 20010321; GB 9809350 D0 19980701; HU 0102394 A2 20011228; HU 0102394 A3 20030128; IL 139405 D0 20011125; JP 2002513789 A 20020514; NO 20005498 A 20001101; NO 20005498 D0 20001101; PL 343705 A1 20010827; SK 16522000 A3 20010510; ZA 200006036 B 20020125

INPADOC legal status


2007-12-07 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1036620

2007-11-14 [RTI1] TITLE (CORRECTION)

- Free text: REDUCED PARTICLE SIZE FORM OF 1-(6-CHLORONAPHTH-2- YLSULPHONYL) -4- 4-(4PYRIDYL) BENZOYL PIPERAZINE

2004-05-19 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031101

2001-03-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001204

2001-03-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-03-21 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001204;LT PAYMENT 20001204;LV PAYMENT 20001204;MK PAYMENT 20001204;RO PAYMENT 20001204;SI PAYMENT 20001204