EP 1084140 A1 20010321 - PREPARATION AND PURIFICATION OF A SALT OF ASPARTAME WITH ACESULFAM K
Title (en)
PREPARATION AND PURIFICATION OF A SALT OF ASPARTAME WITH ACESULFAM K
Title (de)
BEREITSTELLUNG UND REINIGUNG EINES SALZES VON ASPARTAM MIT ACESULFAM-K
Title (fr)
PREPARATION ET PURIFICATION D'UN SEL ORGANIQUE D'ASPARTAME AU MOYEN D'ACESULFAME-K
Publication
Application
Priority
- NL 9900339 W 19990601
- NL 1009323 A 19980605
Abstract (en)
[origin: WO9964445A1] The invention relates to a process for the preparation of the salt of aspartame and acesulphamic acid wherein the salt of aspartame and acesulphamic acid is made available as a wet solid crystalline product which upon drying results in a product having a particle-size distribution in which at least 10 wt.% of the particles is larger than 200 mu m. This crystalline product has an improved stability as compared with the product of the state of the art. In one embodiment the wet solid crystalline product is also subjected, prior to the drying operation, to a washing operation with a basic aqueous solution having a pH of 8 or higher. The invention also relates to the salt of aspartame and acesulphamic acid having such an increased stability that the acetoacetamide content upon heating of that salt in dry form at a temperature of 80 DEG C for 48 hours remains lower than 10 ppm relative to the dry weight of the salt. In dried form, such salt of aspartame and acesulphamic acid has a particle-size distribution in which at least 10 wt.%, and more in particular at least 25 wt.%, of the particles is larger than 200 mu m.
IPC 1-7
IPC 8 full level
A23L 27/30 (2016.01); C07K 5/075 (2006.01)
CPC (source: EP KR)
A23L 27/32 (2016.07 - EP); C07K 5/0613 (2013.01 - EP KR)
Citation (search report)
See references of WO 9964445A1
Designated contracting state (EPC)
DE FR GB NL
DOCDB simple family (publication)
WO 9964445 A1 19991216; AU 4173899 A 19991230; CN 1304415 A 20010718; EP 1084140 A1 20010321; JP 2002517511 A 20020618; KR 20010052586 A 20010625; NL 1009323 C2 19991207
DOCDB simple family (application)
NL 9900339 W 19990601; AU 4173899 A 19990601; CN 99807050 A 19990601; EP 99925472 A 19990601; JP 2000553453 A 19990601; KR 20007013767 A 20001205; NL 1009323 A 19980605