Global Patent Index - EP 1084253 A1

EP 1084253 A1 20010321 - HIV VIRUS MIMOTOPES

Title (en)

HIV VIRUS MIMOTOPES

Title (de)

MIMOTOPE DES HIV VIRUS

Title (fr)

MIMOTOPES DU VIRUS HIV

Publication

EP 1084253 A1 20010321 (FR)

Application

EP 99925080 A 19990614

Priority

  • FR 9901409 W 19990614
  • FR 9807598 A 19980612

Abstract (en)

[origin: WO9966046A1] The invention concerns a peptide for therapeutic or prophylactic treatment of HIV infection, capable of reacting with an antibody specific of the HIV virus envelope and derived from a HIV positive patient belonging to the long term non-progressor group, comprising an amino acid sequence mimicking an antigen conformational epitope of said virus envelope without however corresponding to a continuous sequence of said antigen and capable of containing optionally one of the 11 amino acid sequences as specified in the description. The invention also concerns a peptide conjugate obtained by combining the peptide with a carrier molecule for reinforcing said peptide immunogenicity. The invention further concerns a recombinant vector comprising a functional expression cassette for expressing a polynucleotide coding for said peptide. The invention likewise concerns a therapeutic or prophylactic composition for HIV infection, in particular for vaccinal use, whereof the principle comprises said peptide, or as the case may be said peptide conjugate and/or a recombinant vector coding for said peptide. Finally the invention concerns the use of said peptide as reagent for diagnosing HIV infection and/or the proneness of subjects in contact with the virus for rapidly developing AIDS.

IPC 1-7

C12N 15/49; C07K 14/16; A61K 39/21; C12N 15/63

IPC 8 full level

C07K 14/16 (2006.01); C12N 15/49 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP)

C07K 14/005 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); C12N 2740/16122 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9966046 A1 19991223; AU 4148999 A 20000105; AU 748700 B2 20020613; CA 2331197 A1 19991223; EP 1084253 A1 20010321; NZ 508812 A 20021126

DOCDB simple family (application)

FR 9901409 W 19990614; AU 4148999 A 19990614; CA 2331197 A 19990614; EP 99925080 A 19990614; NZ 50881299 A 19990614