Global Patent Index - EP 1084253 A1

EP 1084253 A1 2001-03-21 - HIV VIRUS MIMOTOPES

Title (en)

HIV VIRUS MIMOTOPES

Title (de)

MIMOTOPE DES HIV VIRUS

Title (fr)

MIMOTOPES DU VIRUS HIV

Publication

EP 1084253 A1 (FR)

Application

EP 99925080 A

Priority

  • FR 9901409 W
  • FR 9807598 A

Abstract (en)

[origin: WO9966046A1] The invention concerns a peptide for therapeutic or prophylactic treatment of HIV infection, capable of reacting with an antibody specific of the HIV virus envelope and derived from a HIV positive patient belonging to the long term non-progressor group, comprising an amino acid sequence mimicking an antigen conformational epitope of said virus envelope without however corresponding to a continuous sequence of said antigen and capable of containing optionally one of the 11 amino acid sequences as specified in the description. The invention also concerns a peptide conjugate obtained by combining the peptide with a carrier molecule for reinforcing said peptide immunogenicity. The invention further concerns a recombinant vector comprising a functional expression cassette for expressing a polynucleotide coding for said peptide. The invention likewise concerns a therapeutic or prophylactic composition for HIV infection, in particular for vaccinal use, whereof the principle comprises said peptide, or as the case may be said peptide conjugate and/or a recombinant vector coding for said peptide. Finally the invention concerns the use of said peptide as reagent for diagnosing HIV infection and/or the proneness of subjects in contact with the virus for rapidly developing AIDS.

IPC 1-7 (main, further and additional classification)

C12N 15/49; A61K 39/21; C07K 14/16; C12N 15/63

IPC 8 full level (invention and additional information)

C07K 14/16 (2006.01); C12N 15/49 (2006.01); A61K 39/00 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); C12N 2740/16122 (2013.01)

Citation (search report)

See references of WO 9966046A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9966046 A1 19991223; AU 4148999 A 20000105; AU 748700 B2 20020613; CA 2331197 A1 19991223; EP 1084253 A1 20010321; NZ 508812 A 20021126

INPADOC legal status


2004-08-11 [18W] WITHDRAWN

- Effective date: 20040616

2003-09-24 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030808

2001-03-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010112

2001-03-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE