EP 1085895 A1 20010328 - BRADYKININ ANTAGONISTS
Title (en)
BRADYKININ ANTAGONISTS
Title (de)
BRADYKININ-ANTAGONISTEN
Title (fr)
ANTAGONISTES DE BRADYKININE
Publication
Application
Priority
- US 9912674 W 19990607
- US 8846698 P 19980608
- US 9293898 P 19980715
- US 12575199 P 19990323
Abstract (en)
[origin: WO9964039A1] Disclosed are multibinding compounds which are bradykinin antagonists. The multibinding compounds of this invention contain from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a bradykinin antagonist. The multibinding compounds of this invention are useful in the treatment and prevention of diseases such as cancer, pain, shock, asthma, rhinitis, arthritis, inflammatory bowel disease, and the like.
IPC 1-7
A61K 38/00; A61K 39/00; A61K 39/44; A61K 39/395; A61K 51/00; C07K 2/00; C07K 4/00; G01N 33/53; G01N 33/543; G01N 33/566
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/4184 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01); A61K 51/00 (2006.01); A61P 1/04 (2006.01); A61P 9/02 (2006.01); A61P 11/06 (2006.01); A61P 19/02 (2006.01); A61P 25/04 (2006.01); A61P 27/16 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 211/90 (2006.01); C07D 215/24 (2006.01); C07D 235/26 (2006.01); C07D 241/42 (2006.01); C07D 471/04 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61K 47/55 (2017.07); A61P 1/18 (2017.12); A61P 11/08 (2017.12); C07D 215/26 (2013.01); C07D 241/42 (2013.01); C07D 471/04 (2013.01); G01N 33/94 (2013.01); G01N 2500/02 (2013.01)
Citation (search report)
See references of WO 9964039A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9964039 A1 19991216; WO 9964039 A9 20001012; AU 4335299 A 19991230; CA 2319730 A1 19991216; EP 1085895 A1 20010328; JP 2002517461 A 20020618
DOCDB simple family (application)
US 9912674 W 19990607; AU 4335299 A 19990607; CA 2319730 A 19990607; EP 99955429 A 19990607; JP 2000553107 A 19990607