Global Patent Index - EP 1085895 A1

EP 1085895 A1 2001-03-28 - BRADYKININ ANTAGONISTS

Title (en)

BRADYKININ ANTAGONISTS

Title (de)

BRADYKININ-ANTAGONISTEN

Title (fr)

ANTAGONISTES DE BRADYKININE

Publication

EP 1085895 A1 (EN)

Application

EP 99955429 A

Priority

  • US 9912674 W
  • US 8846698 P
  • US 9293898 P
  • US 12575199 P

Abstract (en)

[origin: WO9964039A1] Disclosed are multibinding compounds which are bradykinin antagonists. The multibinding compounds of this invention contain from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a bradykinin antagonist. The multibinding compounds of this invention are useful in the treatment and prevention of diseases such as cancer, pain, shock, asthma, rhinitis, arthritis, inflammatory bowel disease, and the like.

IPC 1-7 (main, further and additional classification)

A61K 38/00; A61K 39/00; A61K 39/395; A61K 39/44; A61K 51/00; C07K 2/00; C07K 4/00; G01N 33/53; G01N 33/543; G01N 33/566

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); A61K 31/00 (2006.01); A61K 31/4184 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01); A61K 51/00 (2006.01); A61P 1/04 (2006.01); A61P 9/02 (2006.01); A61P 11/06 (2006.01); A61P 19/02 (2006.01); A61P 25/04 (2006.01); A61P 27/16 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 211/90 (2006.01); C07D 215/24 (2006.01); C07D 235/26 (2006.01); C07D 241/42 (2006.01); C07D 471/04 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01)

CPC (invention and additional information)

A61K 31/00 (2013.01); A61K 31/4184 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/498 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61K 39/395 (2013.01); A61K 39/44 (2013.01); A61K 51/00 (2013.01); C07D 211/90 (2013.01); C07D 215/24 (2013.01); C07D 235/26 (2013.01); C07D 241/42 (2013.01); C07D 471/04 (2013.01); C07K 2/00 (2013.01); C07K 4/00 (2013.01); G01N 33/53 (2013.01); G01N 33/543 (2013.01); G01N 33/566 (2013.01)

Citation (search report)

See references of WO 9964039A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9964039 A1 19991216; WO 9964039 A9 20001012; AU 4335299 A 19991230; CA 2319730 A1 19991216; EP 1085895 A1 20010328; JP 2002517461 A 20020618

INPADOC legal status


2004-07-14 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040103

2002-07-17 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: THERAVANCE, INC.

2001-03-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010108

2001-03-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE