EP 1086066 A1 20010328 - MUSCARINIC RECEPTOR ANTAGONISTS
Title (en)
MUSCARINIC RECEPTOR ANTAGONISTS
Title (de)
MUSKARINREZEPTORANTAGONISTEN
Title (fr)
ANTAGONISTES DES RECEPTEURS MUSCARINIQUES
Publication
Application
Priority
- US 9912733 W 19990607
- US 8846698 P 19980608
- US 9293898 P 19980715
- US 12028799 P 19990216
Abstract (en)
[origin: WO9964043A1] Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscarinic receptor antagonist or an allosteric modulator provided that at least one of said ligand is a muscarinic receptor antagonist. The multibinding compounds of this invention are useful in the treatment and prevention of diseases such as chronic obstructive pulmonary disease, chronic bronchitis, irritable bowel syndrome, urinary incontinence, and the like.
IPC 1-7
C07B 61/00; A61K 38/00; A61K 39/00; A61K 39/44; A61K 39/395; A61K 51/00; G01N 33/53; G01N 33/543; G01N 33/566
IPC 8 full level
G01N 33/53 (2006.01); A01N 43/00 (2006.01); A01N 55/02 (2006.01); A61K 31/135 (2006.01); A61K 31/33 (2006.01); A61K 31/40 (2006.01); A61K 31/404 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/445 (2006.01); A61K 31/45 (2006.01); A61K 31/4523 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/455 (2006.01); A61K 31/498 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01); A61K 51/00 (2006.01); A61P 1/04 (2006.01); A61P 1/06 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 13/00 (2006.01); A61P 43/00 (2006.01); C07B 61/00 (2006.01); C07C 217/10 (2006.01); C07D 207/08 (2006.01); C07D 209/00 (2006.01); C07D 209/32 (2006.01); C07D 209/48 (2006.01); C07D 211/00 (2006.01); C07D 211/44 (2006.01); C07D 211/46 (2006.01); C07D 221/24 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 451/00 (2006.01); C07D 451/06 (2006.01); C07D 451/10 (2006.01); C07D 487/18 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/02 (2006.01); C40B 20/00 (2006.01); C40B 40/02 (2006.01); C40B 40/04 (2006.01); C40B 50/06 (2006.01); C40B 60/10 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/04 (2017.12); A61P 1/06 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 13/00 (2017.12); A61P 43/00 (2017.12); C07D 209/32 (2013.01); C07D 211/12 (2013.01); C07D 211/44 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9964043 A1 19991216; WO 9964043 A9 20000302; AR 018629 A1 20011128; AU 4550899 A 19991230; AU 763638 B2 20030731; CA 2315883 A1 19991216; EP 1086066 A1 20010328; EP 1086066 A4 20010808; JP 2002517464 A 20020618; NZ 505329 A 20030530; SG 80041 A1 20010417
DOCDB simple family (application)
US 9912733 W 19990607; AR P990102700 A 19990608; AU 4550899 A 19990607; CA 2315883 A 19990607; EP 99928444 A 19990607; JP 2000553111 A 19990607; NZ 50532999 A 19990607; SG 1999002762 A 19990607