Global patent index - EP 1086088 A2

EP 1086088 A2 2001-03-28 - NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS

Title (en)

NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS

Title (de)

NEUE NEUROKININANTAGONISTEN, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN

Title (fr)

NOUVEAUX ANTAGONISTES DE LA NEUROKININE, LEUR PROCEDE DE PRODUCTION ET COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES

Publication

EP 1086088 A2 (DE)

Application

EP 99926368 A

Priority

  • DE 19824470 A
  • EP 9903531 W

Abstract (en)

[origin: DE19824470A1] The invention relates to novel compounds of general formula (I) or the pharmaceutically acceptable salts thereof, wherein X = N-R<3> or CH-R<4>, Y = CH2 or (CH2)2, Z = O or H2; and R<1>, R<2>, R<3>, R<4> and Ar have the meaning cited in the description. The invention also relates to the production and use thereof. The novel compounds are valuable neurokinin (tachykinin) antagonists.

IPC 1-7 (main, further and additional classification)

C07D 295/215; A61K 31/495; C07D 233/48

IPC 8 full level (invention and additional information)

C07D 295/14 (2006.01); A61K 31/4427 (2006.01); A61K 31/4468 (2006.01); A61K 31/4545 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61P 43/00 (2006.01); C07D 211/58 (2006.01); C07D 233/44 (2006.01); C07D 233/46 (2006.01); C07D 233/48 (2006.01); C07D 233/54 (2006.01); C07D 239/12 (2006.01); C07D 295/215 (2006.01); C07D 401/12 (2006.01)

CPC (invention and additional information)

C07D 295/215 (2013.01); C07D 233/44 (2013.01); C07D 239/12 (2013.01); C07C 2101/14 (2013.01)

Citation (search report)

See references of WO 9962893A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

DE 19824470 A1 19991202; CA 2333689 A1 19991209; EP 1086088 A2 20010328; JP 2002517386 A 20020618; US 2002010173 A1 20020124; US 2002133012 A1 20020919; US 2002147359 A1 20021010; US 6103719 A 20000815; US 6277840 B1 20010821; US 6429328 B2 20020806; US 6455700 B1 20020924; WO 9962893 A2 19991209; WO 9962893 A3 20000309

INPADOC legal status

2004-06-09 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20031202

2003-03-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG

- Ref Legal Event Code: RAP1

2001-03-28 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20010102

2001-03-28 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE