Global Patent Index - EP 1086134 A2

EP 1086134 A2 2001-03-28 - METHODS TO PREPARE ANTIBODIES WHICH BIND TO POSTTRANSLATIONALLY MODIFIED AMINO ACIDS WITHIN PEPTIDES

Title (en)

METHODS TO PREPARE ANTIBODIES WHICH BIND TO POSTTRANSLATIONALLY MODIFIED AMINO ACIDS WITHIN PEPTIDES

Title (de)

HERSTELLUNGSVERFAHREN FÜR ANTIKÖRPER DIE POSTTRANSLATIONAL MODIFIZIERTE AMINOSÄUREN INNERHALB VON PEPTIDEN BINDEN

Title (fr)

PREPARATION D'ANTICORPS SE LIANT A DES ACIDES AMINES MODIFIES APRES TRADUCTION A L'INTERIEUR DE PEPTIDES

Publication

EP 1086134 A2 (EN)

Application

EP 99957063 A

Priority

  • GB 9901795 W
  • GB 9812772 A
  • GB 9819945 A

Abstract (en)

[origin: WO9965946A2] The invention relates to a process for preparing a spectrum of antibodies by use of a peptide library as an immunogenic substrate. Such antibody spectra are useful in that they may be used to identify, localise or measure amino acids within peptides involved in post-translational modifications and, consequently, may be used in screening for inhibitors of enzymes which are involved in such post-translational modifications. In particular the invention relates to preparing a spectrum of antibodies raised using a peptide library in which the majority of peptides contain a consensus sequence for a domain within which a serine or threonine is phosphorylated, where such a spectrum or part thereof is useful in screening, particularly in a high throughput manner, for inhibitors of serine or threonine kinase.

IPC 1-7 (main, further and additional classification)

C07K 16/00

IPC 8 full level (invention and additional information)

C07K 16/00 (2006.01)

CPC (invention and additional information)

C07K 16/00 (2013.01)

Citation (search report)

See references of WO 9965946A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9965946 A2 19991223; WO 9965946 A3 20000203; EP 1086134 A2 20010328

INPADOC legal status


2005-08-10 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050203

2004-11-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040922

2001-03-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010115

2001-03-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE