EP 1086134 A2 20010328 - METHODS TO PREPARE ANTIBODIES WHICH BIND TO POSTTRANSLATIONALLY MODIFIED AMINO ACIDS WITHIN PEPTIDES
Title (en)
METHODS TO PREPARE ANTIBODIES WHICH BIND TO POSTTRANSLATIONALLY MODIFIED AMINO ACIDS WITHIN PEPTIDES
Title (de)
HERSTELLUNGSVERFAHREN FÜR ANTIKÖRPER DIE POSTTRANSLATIONAL MODIFIZIERTE AMINOSÄUREN INNERHALB VON PEPTIDEN BINDEN
Title (fr)
PREPARATION D'ANTICORPS SE LIANT A DES ACIDES AMINES MODIFIES APRES TRADUCTION A L'INTERIEUR DE PEPTIDES
Publication
Application
Priority
- GB 9901795 W 19990608
- GB 9812772 A 19980613
- GB 9819945 A 19980915
Abstract (en)
[origin: WO9965946A2] The invention relates to a process for preparing a spectrum of antibodies by use of a peptide library as an immunogenic substrate. Such antibody spectra are useful in that they may be used to identify, localise or measure amino acids within peptides involved in post-translational modifications and, consequently, may be used in screening for inhibitors of enzymes which are involved in such post-translational modifications. In particular the invention relates to preparing a spectrum of antibodies raised using a peptide library in which the majority of peptides contain a consensus sequence for a domain within which a serine or threonine is phosphorylated, where such a spectrum or part thereof is useful in screening, particularly in a high throughput manner, for inhibitors of serine or threonine kinase.
IPC 1-7
IPC 8 full level
C07K 16/00 (2006.01)
CPC (source: EP)
C07K 16/00 (2013.01)
Citation (search report)
See references of WO 9965946A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9965946 A2 19991223; WO 9965946 A3 20000203; EP 1086134 A2 20010328
DOCDB simple family (application)
GB 9901795 W 19990608; EP 99957063 A 19990608