Global Patent Index - EP 1086136 A1

EP 1086136 A1 2001-03-28 - MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES

Title (en)

MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES

Title (de)

MONOKLONALE ANTIKÖRPER SPEZIFISCH FÜR DER DERIVATE GUANIDIN-GRUPPEN FORTGESCHRITTENER GLYKOSILIERUNGS ENDPRODUKTE IN BIOLOGISCHEN PROBEN

Title (fr)

ANTICORPS MONOCLONAUX SPECIFIQUES DE PRODUITS FINAUX DE GLYCOSYLATION AVANCEE DERIVES DE GROUPES GUANIDINO DANS DES ECHANTILLONS BIOLOGIQUES

Publication

EP 1086136 A1 (EN)

Application

EP 99928516 A

Priority

  • US 9912969 W
  • US 9379998 A

Abstract (en)

[origin: WO9964463A1] The present invention relates to monoclonal antibodies to guanidino group-derived advanced glycosylation endproducts formed in vivo and cross-reactive with advanced glycosylation endproducts formed in vitro, and to methods of diagnosis and therapy based thereon. More particularly, the invention is directed to a monoclonal antibody, or an antigen-binding fragment thereof, reactive with in vivo produced advanced glycosylation endproducts (AGEs), which monoclonal antibody or antigen binding fragment thereof demonstrates an immunological binding characteristic of monoclonal antibody 4E1 as produced by hybridoma F52-4E1, deposited with the American Type Culture Collection (ATCC) on March 31, 1998, and assigned Accession Number HB-12500.

IPC 1-7 (main, further and additional classification)

C07K 16/18; A61K 38/17; A61K 39/395; C12N 5/20; G01N 33/543; G01N 33/577; G01N 33/58; G01N 33/68

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 43/00 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12N 5/20 (2006.01); C12N 15/02 (2006.01); C12P 21/08 (2006.01); G01N 33/577 (2006.01); G01N 33/66 (2006.01); C12R 1/91 (2006.01)

CPC (invention and additional information)

C07K 16/18 (2013.01); G01N 33/66 (2013.01); A61K 38/00 (2013.01); C07K 2317/24 (2013.01)

Citation (search report)

See references of WO 9964463A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9964463 A1 19991216; AU 4556699 A 19991230; EP 1086136 A1 20010328; JP 2002517224 A 20020618

INPADOC legal status


2005-08-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050104

2001-03-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010108

2001-03-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-03-28 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20010108;LT PAYMENT 20010108;LV PAYMENT 20010108;MK PAYMENT 20010108;RO PAYMENT 20010108;SI PAYMENT 20010108