EP 1086136 A1 20010328 - MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES
Title (en)
MONOCLONAL ANTIBODIES SPECIFIC FOR GUANIDINO GROUP-DERIVED ADVANCED GLYCOSYLATION ENDPRODUCTS IN BIOLOGICAL SAMPLES
Title (de)
MONOKLONALE ANTIKÖRPER SPEZIFISCH FÜR DER DERIVATE GUANIDIN-GRUPPEN FORTGESCHRITTENER GLYKOSILIERUNGS ENDPRODUKTE IN BIOLOGISCHEN PROBEN
Title (fr)
ANTICORPS MONOCLONAUX SPECIFIQUES DE PRODUITS FINAUX DE GLYCOSYLATION AVANCEE DERIVES DE GROUPES GUANIDINO DANS DES ECHANTILLONS BIOLOGIQUES
Publication
Application
Priority
- US 9912969 W 19990609
- US 9379998 A 19980609
Abstract (en)
[origin: WO9964463A1] The present invention relates to monoclonal antibodies to guanidino group-derived advanced glycosylation endproducts formed in vivo and cross-reactive with advanced glycosylation endproducts formed in vitro, and to methods of diagnosis and therapy based thereon. More particularly, the invention is directed to a monoclonal antibody, or an antigen-binding fragment thereof, reactive with in vivo produced advanced glycosylation endproducts (AGEs), which monoclonal antibody or antigen binding fragment thereof demonstrates an immunological binding characteristic of monoclonal antibody 4E1 as produced by hybridoma F52-4E1, deposited with the American Type Culture Collection (ATCC) on March 31, 1998, and assigned Accession Number HB-12500.
IPC 1-7
C07K 16/18; C12N 5/20; G01N 33/577; G01N 33/58; A61K 39/395; A61K 38/17; G01N 33/68; G01N 33/543
IPC 8 full level
A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61P 43/00 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12N 5/20 (2006.01); C12N 15/02 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); G01N 33/66 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 43/00 (2017.12); C07K 16/18 (2013.01); G01N 33/66 (2013.01); A61K 38/00 (2013.01); C07K 2317/24 (2013.01)
Citation (search report)
See references of WO 9964463A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9964463 A1 19991216; AU 4556699 A 19991230; EP 1086136 A1 20010328; JP 2002517224 A 20020618
DOCDB simple family (application)
US 9912969 W 19990609; AU 4556699 A 19990609; EP 99928516 A 19990609; JP 2000553469 A 19990609