EP 1087698 A4 20030903 - DETECTION OF CANCER USING CELLULAR AUTOFLUORESCENCE
Title (en)
DETECTION OF CANCER USING CELLULAR AUTOFLUORESCENCE
Title (de)
KREBSERKENNUNG MITTELS ZELLULÄRER AUTOFLUORESZENS
Title (fr)
DETECTION DE CANCERS A L'AIDE DE L'AUTOFLUORESCENCE CELLULAIRE
Publication
Application
Priority
- US 9817597 W 19980825
- US 9793198 A 19980616
Abstract (en)
[origin: WO9965394A1] Apparatus and methods especially useful for detection of cancer using cellular autofluorescence are described. In one embodiment, an apparatus (10) includes a source (12) of white light which produces a beam of light transmitted to a tissue via one group (18) of optic fibers in a two-way fiber optic bundle (22). The two-way fiber optic bundle (22) may be passed through a conventional endoscope. The beam of light excites the tissue and results in an emission of cellular autofluorescence at a wavelength of about 330 nm. A light sample from the tissue is directed back through the two-way fiber optic bundle (22) and then passes through a photodetector (36). The photodetector (36) produces a signal, representative of the intensity of cellular autofluorescence, which can be passed to a monitor (38) as a wave form or meter response. The apparatus may further comprise a charge-coupled device and video imaging technology to produce real time video images of tissue being examined.
IPC 1-7
IPC 8 full level
G01N 21/64 (2006.01); A61B 1/00 (2006.01); A61B 5/00 (2006.01); G01N 33/50 (2006.01); G01N 33/533 (2006.01)
CPC (source: EP)
A61B 5/0071 (2013.01); A61B 5/0084 (2013.01); G01N 33/5005 (2013.01); G01N 33/533 (2013.01); A61B 5/4233 (2013.01); A61B 5/4331 (2013.01); A61B 5/4375 (2013.01); A61B 5/441 (2013.01)
Citation (search report)
- [XY] US 5131398 A 19920721 - ALFANO ROBERT R [US], et al
- [Y] US 5612540 A 19970318 - RICHARDS-KORTUM REBECCA [US], et al
- [Y] US 5507287 A 19960416 - PALCIC BRANKO [CA], et al
- See references of WO 9965394A1
Designated contracting state (EPC)
DE ES FR GB IT
DOCDB simple family (publication)
WO 9965394 A1 19991223; AU 9119498 A 20000105; CA 2335246 A1 19991223; CN 1301137 A 20010627; EP 1087698 A1 20010404; EP 1087698 A4 20030903; JP 2002518664 A 20020625
DOCDB simple family (application)
US 9817597 W 19980825; AU 9119498 A 19980825; CA 2335246 A 19980825; CN 98814168 A 19980825; EP 98943383 A 19980825; JP 2000554277 A 19980825