Global Patent Index - EP 1087764 A1

EP 1087764 A1 2001-04-04 - THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY

Title (en)

THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY

Title (de)

THERAPEUTISCHE KOMBINATIONEN AUS (SELEKTIVE) ESTROGEN-REZEPTOR MODULATOREN (SERM) UND WACHSTUMSHORMONSEKRETIONSFÖRDERER (GHS) ZUR BEHANDLUNG VON MUSKELSKELETT-GEBRECHLICHKEIT

Title (fr)

TRAITEMENT ASSOCIE DE LA FRAGILITE MUSCULO-SQUELETTIQUE A BASE DE MODULATEUR (SELECTIFS) DE RECEPTEURS D'OESTROGENE ET DE SECRETAGOGUES D'HORMONE DE CROISSANCE

Publication

EP 1087764 A1 (EN)

Application

EP 99923802 A

Priority

  • IB 9901117 W
  • US 8946998 P

Abstract (en)

[origin: WO9965486A1] This invention is directed to pharmaceutical combination compositions and methods containing (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6,7,8-tetrahydronaphthalene-2-ol or a pharmaceutically acceptable salt thereof and 2-amino-N-(2-(3a(R)-benzyl-2-methyl-3-oxo-2,3, 3a, 4,6,7-hexahydro-pyrazolo-[4,3-c]pyridin-5-yl)-1(R)-benzyloxymethyl-2-oxo-ethyl)-isobutyramide or a pharmaceutically acceptable salt thereof, methods of using such compositions and kits containing such compositions. The compositions are useful for treating musculoskeletal frailty, including osteoporosis, osteoporotic fracture, low bone mass, frailty and low muscle mass.

IPC 1-7 (main, further and additional classification)

A61K 31/435

IPC 8 full level (invention and additional information)

A61K 31/437 (2006.01); A61K 31/16 (2006.01); A61K 31/40 (2006.01); A61K 31/402 (2006.01); A61K 31/4162 (2006.01); A61K 31/435 (2006.01); A61P 1/02 (2006.01); A61P 19/00 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); A61P 43/00 (2006.01)

IPC 8 main group level (invention and additional information)

A61K (2006.01); C07C (2006.01)

CPC (invention and additional information)

A61K 31/435 (2013.01)

Combination set (CPC)

  1. A61K 31/435 + A61K 31/40
  2. A61K 31/435 + A61K 2300/00

Citation (search report)

See references of WO 9965486A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9965486 A1 19991223; AP 9901582 D0 19990630; AR 018869 A1 20011212; AU 4054799 A 20000105; BG 105041 A 20010831; BR 9911324 A 20010403; CA 2335134 A1 19991223; CN 1301160 A 20010627; CO 5070587 A1 20010828; EA 200001186 A1 20010625; EP 1087764 A1 20010404; GT 199900087 A 20001207; HN 1999000097 A 19991103; HR P20000859 A2 20010430; HU 0102505 A2 20011128; HU 0102505 A3 20021228; ID 27599 A 20010412; IL 138630 D0 20011031; IS 5691 A 20001027; JP 2002518326 A 20020625; MA 26652 A1 20041220; NO 20006312 A 20001212; NO 20006312 D0 20001212; OA 11505 A 20040507; PA 8475901 A1 20000524; PE 06462000 A1 20000805; PL 344981 A1 20011119; SK 18912000 A3 20011008; TN SN99124 A1 20030403; TR 200003544 T2 20010420; ZA 9903975 B 20001215

INPADOC legal status


2003-07-09 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030103

2001-04-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001206

2001-04-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-04-04 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20001206;LT PAYMENT 20001206;LV PAYMENT 20001206;MK PAYMENT 20001206;RO PAYMENT 20001206;SI PAYMENT 20001206