EP 1087958 B1 20020904 - PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES
Title (en)
PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES
Title (de)
VERFAHREN ZU HERSTELLUNG VON SIMVASTATIN UND ZWISCHENPRODUKTEN
Title (fr)
PROCEDE DE PREPARATION DE SIMVASTATINE ET DE SES PRODUITS INTERMEDIAIRES
Publication
Application
Priority
- CA 9900540 W 19990610
- CA 2240983 A 19980618
Abstract (en)
[origin: US6506929B1] A process is disclosed for the preparation of simvastatin which enables highly regio selective C-methylation of the 2'-position group of lovastatin without requiring protection/deprotection of 13-OH of lovastatin and lactone ring opening/closure.
IPC 1-7
IPC 8 full level
C07D 309/10 (2006.01); C07D 309/30 (2006.01)
CPC (source: EP US)
C07D 309/10 (2013.01 - EP US); C07D 309/30 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9965892 A1 19991223; AT E223397 T1 20020915; CA 2240983 A1 19991218; DE 69902788 D1 20021010; DE 69902788 T2 20030814; EP 1087958 A1 20010404; EP 1087958 B1 20020904; ES 2183559 T3 20030316; US 6506929 B1 20030114
DOCDB simple family (application)
CA 9900540 W 19990610; AT 99924627 T 19990610; CA 2240983 A 19980618; DE 69902788 T 19990610; EP 99924627 A 19990610; ES 99924627 T 19990610; US 71960601 A 20010424