Global Patent Index - EP 1088079 A2

EP 1088079 A2 2001-04-04 - NEK-RELATED AND BUB1-RELATED PROTEIN KINASES

Title (en)

NEK-RELATED AND BUB1-RELATED PROTEIN KINASES

Title (de)

NEK-VERWANDTE UND BUB1-VERWANDTE PROTEINKINASEN

Title (fr)

KINASES EN RAPPORT AVEC NEK ET AVEC BUB1

Publication

EP 1088079 A2 (EN)

Application

EP 99930298 A

Priority

  • US 9913533 W
  • US 8952098 P
  • US 9826598 P

Abstract (en)

[origin: WO9966051A2] The present invention relates to BUB1 and NEK kinase polypeptides, nucleotide sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various kinase-related diseases and conditions. Through the use of a targeted PCR cloning strategy, the human BUB1 serine/threonine kinase was identified and its protein structure was predicted. Additionally, through the use of a bioinformatics strategy, three mammalian members of the NEK-subfamily of STK's have been identified and their protein structure predicted.

IPC 1-7 (main, further and additional classification)

C12N 15/54; A61K 35/00; C07K 16/40; C12N 9/12; C12N 15/11; C12Q 1/48; C12Q 1/68; G01N 33/50

IPC 8 full level (invention and additional information)

G01N 33/50 (2006.01); A61K 38/45 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); C07K 16/40 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/12 (2006.01); C12N 15/09 (2006.01); C12N 15/54 (2006.01); C12Q 1/48 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C12N 9/1205 (2013.01)

Citation (search report)

See references of WO 9966051A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9966051 A2 19991223; WO 9966051 A3 20000615; AU 4686299 A 20000105; CA 2331889 A1 19991223; EP 1088079 A2 20010404; JP 2002518016 A 20020625

INPADOC legal status


2006-05-17 [18R] REFUSED

- Effective date: 20051216

2003-11-05 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030922

2001-04-04 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20001128

2001-04-04 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE