Global Patent Index - EP 1088226 A1

EP 1088226 A1 20010404 - DETECTION OF APOPTOTIC CELLS IN LIVING NEMATODES

Title (en)

DETECTION OF APOPTOTIC CELLS IN LIVING NEMATODES

Title (de)

NACHWEIS APOPTOTISCHER ZELLEN IN LEBENDEN NEMATODEN

Title (fr)

DETECTION DE CELLULES D'APOPTOSE DANS DES NEMATODES VIVANTS

Publication

EP 1088226 A1 20010404 (EN)

Application

EP 99928736 A 19990618

Priority

  • US 9913650 W 19990618
  • US 9005798 P 19980619

Abstract (en)

[origin: WO9966323A1] The present invention relates to methods and kits for detecting apoptotic cells in a live nematode by exposing the live nematode to a vital dye that stains apoptotic cells, and detecting the apoptotic cells. Applications of this assay include methods of identifying agents, conditions or genes that modulate apoptosis. The present invention also includes methods of screening for mutated nematodes that exhibit altered apoptotic cell death.

IPC 1-7

G01N 33/50

IPC 8 full level

G01N 33/15 (2006.01); G01N 33/50 (2006.01)

CPC (source: EP)

G01N 33/5091 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9966323 A1 19991223; WO 9966323 A9 20000406; AU 4573199 A 20000105; AU 746694 B2 20020502; CA 2335549 A1 19991223; CN 1305588 A 20010725; EP 1088226 A1 20010404; HU P0103709 A2 20020128; JP 2002518674 A 20020625; PL 345518 A1 20011217

DOCDB simple family (application)

US 9913650 W 19990618; AU 4573199 A 19990618; CA 2335549 A 19990618; CN 99807335 A 19990618; EP 99928736 A 19990618; HU P0103709 A 19990618; JP 2000555091 A 19990618; PL 34551899 A 19990618