Global Patent Index - EP 1089756 A4

EP 1089756 A4 20020717 - CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS

Title (en)

CORRELATIVE PROTECTION USING OspA ANTIBODY TITERS

Title (de)

KORRELATIVER SCHUTZ UNTER VERWENDUNG VON OSPA ANTIKÖRPER-TITER

Title (fr)

PROTECTION CORRELATIVE FAISANT APPEL A DES TITRES D'ANTICORPS OspA

Publication

EP 1089756 A4 20020717 (EN)

Application

EP 99925696 A 19990520

Priority

  • US 9911158 W 19990520
  • US 8645698 P 19980522
  • US 12741599 P 19990401

Abstract (en)

[origin: WO9961048A1] Methods of protecting human beings from infection by DOLLAR (B. burgdorferi) are disclosed, which comprises internally administering lipoprotein OspA, or a combination of lipoprotein OspAs using specified dosing schedules.

IPC 1-7

A61K 39/00; A61K 39/38; A61K 39/02; A61K 49/00; G01N 31/00; G01N 33/48; C12N 1/12; C12N 1/20; C07K 1/00; C07K 14/00; C07K 17/00

IPC 8 full level

A61K 39/02 (2006.01); A61P 31/04 (2006.01); G01N 33/569 (2006.01); A61K 38/12 (2006.01)

CPC (source: EP)

A61K 39/0225 (2013.01); A61P 31/04 (2017.12); G01N 33/56911 (2013.01); A61K 38/00 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

  • [X] EP 0812593 A1 19971217 - SMITHKLINE BEECHAM BIOLOG [BE]
  • [X] VAN HOECKE C ET AL: "Evaluation of a lipoprotein OspA vaccine administered following a 0, 1, 2 month primary vaccination course with a booster at month 12.", ABSTRACTS OF THE INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND, vol. 35, 1995, 35th Interscience Conference on Antimicrobial Agents and Chemotherapy;San Francisco, California, USA; September 17-20, 1995, 1995, pages 172, XP001069749
  • [X] KELLER DAVID ET AL: "Safety and immunogenicity of a recombinant outer surface protein A Lyme vaccine.", JAMA (JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION), vol. 271, no. 22, 1994, pages 1764 - 1768, XP001070476, ISSN: 0098-7484
  • [PX] VAN HOECKE C ET AL: "Clinical and immunological assessment of a candidate Lyme disease vaccine in healthy adults: antibody persistence and effect of a booster dose at month 12", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 16, no. 17, 1 October 1998 (1998-10-01), pages 1688 - 1692, XP004139711, ISSN: 0264-410X
  • [T] VAN HOECKE C ET AL: "Alternative vaccination schedules (0, 1, and 6 months versus 0, 1, and 12 months) for a recombinant OspA Lyme disease vaccine.", CLINICAL INFECTIOUS DISEASES, vol. 28, no. 6, June 1999 (1999-06-01), pages 1260 - 1264, XP002197376, ISSN: 1058-4838
  • See references of WO 9961048A1

Designated contracting state (EPC)

BE CH DE ES FR GB IT LI NL

DOCDB simple family (publication)

WO 9961048 A1 19991202; AU 4193399 A 19991213; CA 2332979 A1 19991202; EP 1089756 A1 20010411; EP 1089756 A4 20020717

DOCDB simple family (application)

US 9911158 W 19990520; AU 4193399 A 19990520; CA 2332979 A 19990520; EP 99925696 A 19990520