Global patent index - EP 1089997 A1

EP 1089997 A1 2001-04-11 - 4,5,6 AND 7-INDOLE AND INDOLINE DERIVATIVES, THEIR PREPARATION AND USE

Title (en)

4,5,6 AND 7-INDOLE AND INDOLINE DERIVATIVES, THEIR PREPARATION AND USE

Title (de)

4,5,6 UND 7-INDOL- UND INDOLIN-DERIVATE, IHRE HERSTELLUNG UND ANWENDUNG

Title (fr)

DERIVES DE 4, 5, 6, ET 7-INDOLE OU D'INDOLINE, LEUR PREPARATION, ET LEUR UTILISATION

Publication

EP 1089997 A1 (EN)

Application

EP 99926281 A

Priority

  • DK 9900326 W
  • DK 82098 A
  • US 9282398 P

Abstract (en)

[origin: WO9967237A1] A substituted 4-, 5-, 6-, and 7-indole or indoline derivative of Formula (I) wherein A is a group having formula (IIA), (IIB), (IIC) wherein X, U, Y, R<3> to R<12>, Z, W, n and m are as defined above. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.

IPC 1-7 (main, further and additional classification)

C07D 405/14; A61K 31/445; A61K 31/495; C07D 209/20; C07D 401/14; C07D 405/12

IPC 8 full level (invention and additional information)

A61K 31/4427 (2006.01); A61K 31/443 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61P 25/14 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 43/00 (2006.01); C07D 209/14 (2006.01); C07D 209/16 (2006.01); C07D 209/42 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01)

CPC (invention and additional information)

C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01)

Citation (search report)

See references of WO 9967237A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9967237 A1 19991229; AU 4359299 A 20000110; AU 765317 B2 20030918; AU 765317 C 20040520; BG 105136 A 20010928; CA 2335711 A1 19991229; EP 1089997 A1 20010411; HR P20000847 A2 20011231; HU 0101475 A2 20011028; HU 0101475 A3 20030128; JP 2003521443 A 20030715; NO 20006460 A 20010219; NO 20006460 D0 20001218; NZ 508506 A 20040130

INPADOC legal status

2005-03-02 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040831

2003-03-26 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030206

2001-04-11 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20010119

2001-04-11 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-04-11 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20010119;LT PAYMENT 20010119;LV PAYMENT 20010119;MK PAYMENT 20010119;RO PAYMENT 20010119;SI PAYMENT 20010119