Global patent index - EP 1090003 A1

EP 1090003 A1 2001-04-11 - 7-ALKYL- AND CYCLOALKYL-SUBSTITUTED IMIDAZOTRIAZINONES

Title (en)

7-ALKYL- AND CYCLOALKYL-SUBSTITUTED IMIDAZOTRIAZINONES

Title (de)

7-ALKYL- UND CYCLOALKYL-SUBSTITUIERTE IMIDAZOTRIAZINONE

Title (fr)

IMIDAZOTRIAZINONES A SUBSTITUTION 7-ALKYLE ET CYCLOALKYLE

Publication

EP 1090003 A1 (DE)

Application

EP 99929181 A

Priority

  • DE 19827640 A
  • EP 9904032 W

Abstract (en)

[origin: DE19827640A1] 2-Sulfamoylphenyl-5-alkyl-7-(cyclo)alkyl-4(3H)-imidazo(5,1-f)(1,2,4)tr iazinone derivatives (I) are new. 2-Sulfamoylphenyl-5-alkyl-7-(cyclo)alkyl-4(3H)-imidazo(5,1-f)(1,2,4)tr iazinone derivatives of formula (I) are new: R1 = 1-4C alkyl; R2 = 5-20C alkyl or 3-8C cycloalkyl; R3, R4 = H; 2-8C alkenyl; 1-10C alkyl optionally interrupted by an O atom and optionally substituted by 1-3 of CF3, OCF3, OH, halogen, COOH, benzyloxycarbonyl, 1-6C alkoxy, 2-6C alkoxycarbonyl, 1-6C alkylthio, SO3H, etc; or NR3R4 = optionally substituted optionally benzo-fused 5-7 membered heterocyclic group; or NR3R4 = a (bi)(hetero)cyclic group; and R5, R6 = H, 1-6C alkyl, OH or 1-6C alkoxy. Full definitions given in the 'Definition' section. An Independent claim is also included for the preparation of (I).

IPC 1-7 (main, further and additional classification)

C07D 487/04; A61K 31/53; A61K 31/675; C07F 9/6561

IPC 8 full level (invention and additional information)

A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/539 (2006.01); A61K 31/55 (2006.01); A61K 31/5513 (2006.01); A61K 31/675 (2006.01); A61P 7/12 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 15/00 (2006.01); A61P 15/10 (2006.01); A61P 21/02 (2006.01); A61P 43/00 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); C07F 9/6561 (2006.01)

CPC (invention and additional information)

C07D 487/04 (2013.01); C07F 9/6561 (2013.01)

Citation (search report)

See references of WO 9967244A1

Designated contracting state (EPC)

DE ES FR GB IT

EPO simple patent family

DE 19827640 A1 19991223; AU 4608099 A 20000110; CA 2335193 A1 19991229; EP 1090003 A1 20010411; JP 2002518500 A 20020625; US 2005049250 A1 20050303; US 6476029 B1 20021105; US 6838459 B1 20050104; US 6943163 B2 20050913; WO 9967244 A1 19991229

INPADOC legal status

2012-06-27 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20111231

2004-01-07 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: BAYER HEALTHCARE AG

- Ref Legal Event Code: RAP1

2003-10-01 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030820

2001-04-11 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20010122

2001-04-11 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): DE ES FR GB IT