EP 1090034 A2 20010411 - NOVEL STAPHYLOCOCCUS PEPTIDES FOR BACTERIAL INTERFERENCE
Title (en)
NOVEL STAPHYLOCOCCUS PEPTIDES FOR BACTERIAL INTERFERENCE
Title (de)
NEUE PEPTIDE AUS STAPHYLOCOCCUS ZUR BAKTERIELLEN HEMMUNG
Title (fr)
NOUVEAUX PEPTIDES DE STAPHYLOCOQUES UTILISES POUR DES INTERFERENCES BACTERIENNES
Publication
Application
Priority
- US 9914562 W 19990624
- US 10343898 A 19980624
Abstract (en)
[origin: WO9967286A2] The present invention provides a cyclic peptide comprising structure (I) wherein X is selected from the group consisting of an amino acid, an amino acid analog, a peptidomimetic and a non-amide isostere, Z is selected from the group consisting of a synthetic amino acid and a biosynthetic amino acid, R is selected from the group consisting of oxygen, nitrogen and carbon, n is 0 to 10 and y is 1 to 10. The present invention also provides a cyclic peptide comprising the amino acid sequence of NH2-X(n)-Z-X(y)-COOH and a cyclic bond between the Z residue and COOH other than a thioester bond, wherein X is selected from the group consisting of an amino acid, an amino acid analog, a peptidomimetic and a non-amide isostere, Z is selected from the group consisting of a synthetic amino acid and a biosynthetic amino acid, n is 0 to 10 and y is 1 to 10. Methods of preparation including a cyclization protocol, and methods of use of the cyclic peptides of the invention are also disclosed.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61P 31/04 (2006.01); C07K 14/31 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); C07K 14/31 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9967286A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9967286 A2 19991229; WO 9967286 A3 20000316; WO 9967286 A9 20000504; AU 4723899 A 20000110; AU 769791 B2 20040205; CA 2331888 A1 19991229; EP 1090034 A2 20010411; JP 2002519304 A 20020702
DOCDB simple family (application)
US 9914562 W 19990624; AU 4723899 A 19990624; CA 2331888 A 19990624; EP 99930780 A 19990624; JP 2000555937 A 19990624