Global Patent Index - EP 1090034 A2

EP 1090034 A2 2001-04-11 - NOVEL STAPHYLOCOCCUS PEPTIDES FOR BACTERIAL INTERFERENCE

Title (en)

NOVEL STAPHYLOCOCCUS PEPTIDES FOR BACTERIAL INTERFERENCE

Title (de)

NEUE PEPTIDE AUS STAPHYLOCOCCUS ZUR BAKTERIELLEN HEMMUNG

Title (fr)

NOUVEAUX PEPTIDES DE STAPHYLOCOQUES UTILISES POUR DES INTERFERENCES BACTERIENNES

Publication

EP 1090034 A2 (EN)

Application

EP 99930780 A

Priority

  • US 9914562 W
  • US 10343898 A

Abstract (en)

[origin: WO9967286A2] The present invention provides a cyclic peptide comprising structure (I) wherein X is selected from the group consisting of an amino acid, an amino acid analog, a peptidomimetic and a non-amide isostere, Z is selected from the group consisting of a synthetic amino acid and a biosynthetic amino acid, R is selected from the group consisting of oxygen, nitrogen and carbon, n is 0 to 10 and y is 1 to 10. The present invention also provides a cyclic peptide comprising the amino acid sequence of NH2-X(n)-Z-X(y)-COOH and a cyclic bond between the Z residue and COOH other than a thioester bond, wherein X is selected from the group consisting of an amino acid, an amino acid analog, a peptidomimetic and a non-amide isostere, Z is selected from the group consisting of a synthetic amino acid and a biosynthetic amino acid, n is 0 to 10 and y is 1 to 10. Methods of preparation including a cyclization protocol, and methods of use of the cyclic peptides of the invention are also disclosed.

IPC 1-7 (main, further and additional classification)

C07K 14/31; A61K 38/16

IPC 8 full level (invention and additional information)

A61K 38/00 (2006.01); A61P 31/04 (2006.01); C07K 14/31 (2006.01)

CPC (invention and additional information)

C07K 14/31 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9967286A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9967286 A2 19991229; WO 9967286 A3 20000316; WO 9967286 A9 20000504; AU 4723899 A 20000110; AU 769791 B2 20040205; CA 2331888 A1 19991229; EP 1090034 A2 20010411; JP 2002519304 A 20020702

INPADOC legal status


2007-05-02 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20060829

2003-07-30 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030616

2001-04-11 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20010124

2001-04-11 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE