Global Patent Index - EP 1091976 A2

EP 1091976 A2 2001-04-18 - PEPTIDES FROM VARICELLA-ZOSTER AND OTHER VIRUSES FOR HIV-2 DIAGNOSIS AND THERAPY

Title (en)

PEPTIDES FROM VARICELLA-ZOSTER AND OTHER VIRUSES FOR HIV-2 DIAGNOSIS AND THERAPY

Title (de)

PEPTIDE DES VARIZELLA ZOSTER-VIRUS UND ANDERER VIREN ZUR DIAGNOSE UND THERAPIE VON HIV-2

Title (fr)

PEPTIDES DU VIRUS VARICELLE-ZONA ET AUTRES VIRUS PERMETTANT D'ASSURER UN DIAGNOSTIC ET UNE THERAPIE DANS LE CAS DU VIH-2

Publication

EP 1091976 A2 (EN)

Application

EP 99932223 A

Priority

  • US 9915114 W
  • US 9165998 P
  • US 10468598 P
  • US 11202698 P

Abstract (en)

[origin: WO0001719A2] Viral chimeric peptides useful for HIV diagnostic testing and therapy of HIV are described which comprise a loop sequence from a Varicella-Zoster virus protein and additional portion(s) that enhance antigenic reactivity of the loop with anti-HIV antibody. The peptides typically are at least 16 amino acid residues long and advantageously contain additional portions that have some sequence identity with peptide sequences adjacent to a cystine loop of HIV-1 gp41. The peptides immunologically cross-react with protein from a wide variety of HIV-2 strains. Peptides according to some embodiments of the invention are less hydrophobic and more basic for improved water solubility compared to peptides from naturally occurring strains of HIV. These chimeric peptides differ greatly from the naturally occurring sequences and are not identified as corresponding to any particular viral species or strain.

IPC 1-7 (main, further and additional classification)

C07K 14/00

IPC 8 full level (invention and additional information)

C07K 14/04 (2006.01); C07K 14/16 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); A61K 2039/525 (2013.01); C07K 2319/00 (2013.01); C12N 2710/16722 (2013.01); C12N 2740/16222 (2013.01)

Citation (search report)

See references of WO 0001719A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0001719 A2 20000113; WO 0001719 A3 20000224; AU 4857799 A 20000124; EP 1091976 A2 20010418

INPADOC legal status


2004-05-19 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030201

2001-04-18 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010202

2001-04-18 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-04-18 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI