Global Patent Index - EP 1093519 A2

EP 1093519 A2 2001-04-25 - AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS

Title (en)

AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS

Title (de)

AMPHIPHILE PEPTIDE ABGEGLEITET VOM ZYTOPLASMATISCHEN ENDE DER VIRALEN HÜLLPROTEINE

Title (fr)

PEPTIDES AMPHIPHILES ISOLES DERIVES DE LA QUEUE CYTOPLASMIQUE DE PROTEINES DE L'ENVELOPPE VIRALE

Publication

EP 1093519 A2 (EN)

Application

EP 99926703 A

Priority

  • IB 9901261 W
  • US 11254498 A

Abstract (en)

[origin: WO0002909A2] An isolated peptide comprising an amino acid sequence derived from a viral envelope protein, wherein at least a portion of the amino acid sequence is located within the cytoplasmic tail or membrane-spanning region of a viral envelope protein. Such peptides are amphiphilic in nature, provide for the destabilization of membranes, and facilitate the entry of viral particles into cells and the efficient formation of viral particles. The peptides may, in another embodiment, be attached to the viral membrane, along with a targeting polypeptide, as part of an artificial viral envelope protein.

IPC 1-7 (main, further and additional classification)

C12N 15/48; A61K 38/16; A61K 48/00; C07K 14/15; C12N 5/10; C12N 7/01; C12N 15/86

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); C07K 14/15 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12N 15/867 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); C12N 15/86 (2013.01); C07K 2319/00 (2013.01); C12N 2740/13022 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/40 (2013.01)

Citation (search report)

See references of WO 0002909A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0002909 A2 20000120; WO 0002909 A3 20000504; AU 2003235023 A1 20030911; AU 4386999 A 20000201; CA 2333855 A1 20000120; EP 1093519 A2 20010425; IL 140630 D0 20020210; JP 2003533165 A 20031111

INPADOC legal status


2004-12-29 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040622

2004-01-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031211

2001-04-25 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010111

2001-04-25 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE