EP 1093519 A2 20010425 - AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS
Title (en)
AMPHIPHILIC PEPTIDES DERIVED FROM THE CYTOPLASMIC TAIL OF VIRAL ENVELOPE PROTEINS
Title (de)
AMPHIPHILE PEPTIDE ABGEGLEITET VOM ZYTOPLASMATISCHEN ENDE DER VIRALEN HÜLLPROTEINE
Title (fr)
PEPTIDES AMPHIPHILES ISOLES DERIVES DE LA QUEUE CYTOPLASMIQUE DE PROTEINES DE L'ENVELOPPE VIRALE
Publication
Application
Priority
- IB 9901261 W 19990708
- US 11254498 A 19980709
Abstract (en)
[origin: WO0002909A2] An isolated peptide comprising an amino acid sequence derived from a viral envelope protein, wherein at least a portion of the amino acid sequence is located within the cytoplasmic tail or membrane-spanning region of a viral envelope protein. Such peptides are amphiphilic in nature, provide for the destabilization of membranes, and facilitate the entry of viral particles into cells and the efficient formation of viral particles. The peptides may, in another embodiment, be attached to the viral membrane, along with a targeting polypeptide, as part of an artificial viral envelope protein.
IPC 1-7
C12N 15/48; C07K 14/15; C12N 7/01; A61K 38/16; C12N 15/86; A61K 48/00; C12N 5/10
IPC 8 full level
A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); C07K 14/15 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12N 15/09 (2006.01); C12N 15/867 (2006.01)
CPC (source: EP)
C07K 14/005 (2013.01); C12N 15/86 (2013.01); C07K 2319/00 (2013.01); C12N 2740/13022 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/40 (2013.01)
Citation (search report)
See references of WO 0002909A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0002909 A2 20000120; WO 0002909 A3 20000504; AU 2003235023 A1 20030911; AU 4386999 A 20000201; CA 2333855 A1 20000120; EP 1093519 A2 20010425; IL 140630 A0 20020210; JP 2003533165 A 20031111
DOCDB simple family (application)
IB 9901261 W 19990708; AU 2003235023 A 20030813; AU 4386999 A 19990708; CA 2333855 A 19990708; EP 99926703 A 19990708; IL 14063099 A 19990708; JP 2000559138 A 19990708