EP 1096949 A2 20010509 - TREATMENT OF CELIAC DISEASE WITH INTERLEUKIN-15 ANTAGONISTS
Title (en)
TREATMENT OF CELIAC DISEASE WITH INTERLEUKIN-15 ANTAGONISTS
Title (de)
BEHANDLUNG DER ZÖLIAKIE MIT INTERLEUKIN-15 ANTAGONISTEN
Title (fr)
TRAITEMENT DE LA MALADIE COELIAQUE A L'AIDE D'ANTAGONISTES DE L'INTERLEUKINE-15
Publication
Application
Priority
- GB 9902201 W 19990709
- GB 9814892 A 19980710
Abstract (en)
[origin: WO0002582A2] The invention relates to the treatment of inflammatory bowel diseases, such as celiac disease with interleukin-15 (IL-15) antagonists. Preferably the antagonists are muteins of IL-15, antibodies against IL-15 or IL-15 molecules bound to chemical groups that interfere with the ability of IL-15 to effect a signal transduction through either the beta or gamma -subunit of the IL-15 receptor complex, but which do not interfere with IL-15 binding to IL-15R alpha .
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/20 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 47/48 (2006.01); A61P 1/00 (2006.01); A61P 31/00 (2006.01); A61P 43/00 (2006.01); C07K 16/24 (2006.01)
CPC (source: EP)
A61K 38/2086 (2013.01); A61P 1/00 (2017.12); A61P 31/00 (2017.12); A61P 43/00 (2017.12); C07K 14/5443 (2013.01); C07K 16/244 (2013.01); A61K 9/0031 (2013.01); A61K 9/2004 (2013.01); C07K 2317/76 (2013.01)
Citation (search report)
See references of WO 0002582A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0002582 A2 20000120; WO 0002582 A3 20000316; CA 2333923 A1 20000120; EP 1096949 A2 20010509; GB 9814892 D0 19980909; JP 2002520294 A 20020709
DOCDB simple family (application)
GB 9902201 W 19990709; CA 2333923 A 19990709; EP 99933001 A 19990709; GB 9814892 A 19980710; JP 2000558841 A 19990709