Global Patent Index - EP 1097134 A1

EP 1097134 A1 2001-05-09 - ARYLPIPERAZINE DERIVATIVES USEFUL AS UROSELECTIVE ALPHA1-ADRENOCEPTOR BLOCKERS

Title (en)

ARYLPIPERAZINE DERIVATIVES USEFUL AS UROSELECTIVE ALPHA1-ADRENOCEPTOR BLOCKERS

Title (de)

ARYLPIPERAZIN DERIVATE VERWENDBAR ALS URO-SELECTIEVE ALPHA-1-ADRENOZEPTORENBLOCKERN

Title (fr)

DERIVES D'ARYLPIPERAZINE UTILISES COMME AGENTS BLOQUANTS LES RECEPTEURS ALPHA1-ADRENERGIQUES UROSELECTIFS

Publication

EP 1097134 A1 (EN)

Application

EP 99929633 A

Priority

  • IB 9901296 W
  • IB 9900140 W
  • US 12026598 A

Abstract (en)

[origin: WO0005205A1] Novel piperazine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective alpha 1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.

IPC 1-7 (main, further and additional classification)

C07D 207/40; A61K 31/495; C07D 211/88; C07D 401/06

IPC 8 full level (invention and additional information)

C07D 207/404 (2006.01); C07D 207/408 (2006.01); C07D 211/88 (2006.01); C07D 401/06 (2006.01); C07D 207/40 (2006.01)

CPC (invention and additional information)

C07D 207/404 (2013.01); C07D 207/408 (2013.01); C07D 211/88 (2013.01); C07D 401/06 (2013.01)

Citation (search report)

See references of WO 0005205A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0005205 A1 20000203; AU 4641099 A 20000214; AU 763541 B2 20030724; BR 9912318 A 20010502; CA 2338317 A1 20000203; EP 1097134 A1 20010509; HU 0102980 A2 20011228; HU 0102980 A3 20030228; MX PA01000637 A 20020408; NZ 509388 A 20031219; PL 345562 A1 20011217; SK 932001 A3 20010806

INPADOC legal status


2008-02-22 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1036798

2007-08-01 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20070201

2003-07-30 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030617

2001-05-09 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010221

2001-05-09 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-09 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 20010221;LT PAYMENT 20010221;LV PAYMENT 20010221;MK PAYMENT 20010221;RO PAYMENT 20010221;SI PAYMENT 20010221