EP 1098910 A1 20010516 - ANTIGENIC COMPLEX COMPRISING IMMUNOSTIMULATORY PEPTIDE, CD4, AND CHEMOKINE RECEPTOR DOMAIN FOR HIV TREATMENT AND IMMUNE DISORDERS
Title (en)
ANTIGENIC COMPLEX COMPRISING IMMUNOSTIMULATORY PEPTIDE, CD4, AND CHEMOKINE RECEPTOR DOMAIN FOR HIV TREATMENT AND IMMUNE DISORDERS
Title (de)
ANTIGENER KOMPLEX, DER EIN IMMUNSTIMULIERENDES PEPTID ENTHÄLT, CD4 UND CHEMOKINREZEPTOR-DOMÄNE ZUR BEHANDLUNG VON HIV UND IMMUNERKRANKUNGEN
Title (fr)
COMPLEXE ANTIGENIQUE COMPRENANT UN PEPTIDE IMMUNOSTIMULATEUR, CD4 ET UN DOMAINE DE RECEPTEUR DE CHEMOKINE POUR TRAITER VIH ET DES MALADIES IMMUNITAIRES
Publication
Application
Priority
- US 9914030 W 19990621
- US 10040998 A 19980620
Abstract (en)
[origin: WO9967294A1] The invention provides peptides comprising a sequence homologous to a portion of the CDR-2 like domain of CD4, covalently linked to a helper T cell epitope, and optionally to other immunostimulatory sequences as well. The invention provides for the use of such peptides as immunogens to elicit the production in mammals of high titer polyclonal auto-antibodies, which are specific to CD4 surface complex. These auto-antibodies prevent binding of HIV viral particles to CD4+ cells. The peptides are useful in pharmaceutical compositions, to provide an immunotherapy for HIV infection and to protect against HIV infection.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); C07K 14/705 (2006.01); A61K 39/395 (2006.01); A61P 31/18 (2006.01); A61P 37/04 (2006.01); C07K 14/73 (2006.01); C07K 19/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP US)
A61P 31/18 (2018.01 - EP); A61P 37/04 (2018.01 - EP); C07K 14/70514 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9967294 A1 19991229; AT E447585 T1 20091115; AU 4704899 A 20000110; AU 766955 B2 20031030; BR PI9912175 A 20010410; BR PI9912175 B1 20190827; BR PI9912175 B8 20210706; CA 2330235 A1 19991229; CA 2330235 C 20080812; CN 1207306 C 20050622; CN 1303394 A 20010711; DE 69941625 D1 20091217; DK 1098910 T3 20100201; EP 1098910 A1 20010516; EP 1098910 A4 20050202; EP 1098910 B1 20091104; ES 2336393 T3 20100412; HK 1036805 A1 20020118; JP 2002518523 A 20020625; JP 4216473 B2 20090128; TW I227242 B 20050201; US 6090388 A 20000718; ZA 200006385 B 20011011
DOCDB simple family (application)
US 9914030 W 19990621; AT 99930523 T 19990621; AU 4704899 A 19990621; BR PI9912175 A 19990621; CA 2330235 A 19990621; CN 99806643 A 19990621; DE 69941625 T 19990621; DK 99930523 T 19990621; EP 99930523 A 19990621; ES 99930523 T 19990621; HK 01105568 A 20010810; JP 2000555944 A 19990621; TW 88106132 A 19990416; US 10040998 A 19980620; ZA 200006385 A 20001107