Global Patent Index - EP 1100464 A1

EP 1100464 A1 2001-05-23 - LIPID EMULSION AND SOLID LIPID NANOPARTICLE AS A GENE OR DRUG CARRIER

Title (en)

LIPID EMULSION AND SOLID LIPID NANOPARTICLE AS A GENE OR DRUG CARRIER

Title (de)

LIPIDEMULSION UND FESTE LIPIDNANOTEILCHEN ALS GEN- ODER WIRKSTOFFCARRIER

Title (fr)

EMULSION LIPIDIQUE ET NANOPARTICULE LIPIDIQUE SOLIDE EN TANT QUE TRANSPORTEURS DE GENES OU DE MEDICAMENTS

Publication

EP 1100464 A1 (EN)

Application

EP 99935145 A

Priority

  • KR 9900414 W
  • KR 19980031249 A

Abstract (en)

[origin: WO0006120A1] The present invention relates to oil-in-water lipid emulsions composed of non-triglyceride oils and solid lipid nanoparticles (SLN) composed of triglyceride or ethyl stearate used as gene transfection agents and drug delivery systems and method for preparing thereof. The present invention also concerns the method of transferring genes or drugs efficiently into cells by using the lipid emulsions and solid lipid nanoparticles. Also the present invention relates to the method of preparing lipid emulsions containing lipophilic or amphiphilic drugs by using squalene or squalane as the core-oil. The present invention also concerns the method of preparing the solid lipid nanoparticles containing lipophilic or amphiphilic drugs by using ethyl stearate as the core-fat.

IPC 1-7 (main, further and additional classification)

A61K 9/107

IPC 8 full level (invention and additional information)

A61K 9/10 (2006.01); A61K 9/107 (2006.01); A61K 9/14 (2006.01); A61K 9/51 (2006.01); A61K 31/196 (2006.01); A61K 31/201 (2006.01); A61K 31/203 (2006.01); A61K 31/5585 (2006.01); A61K 31/566 (2006.01); A61K 31/57 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01); A61K 47/18 (2006.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61K 47/30 (2006.01); A61K 47/34 (2006.01); A61K 47/42 (2006.01); A61K 47/44 (2006.01); A61K 47/46 (2006.01); A61K 48/00 (2006.01); A61P 31/12 (2006.01); A61P 37/06 (2006.01); C12N 15/88 (2006.01); A61K 9/127 (2006.01)

CPC (invention and additional information)

A61K 9/5123 (2013.01); A61K 9/1075 (2013.01); A61K 48/00 (2013.01); C12N 15/88 (2013.01); A61K 9/1272 (2013.01)

Citation (search report)

See references of WO 0006120A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0006120 A1 20000210; AU 5068999 A 20000221; EP 1100464 A1 20010523; JP 2002521423 A 20020716; KR 100374482 B1 20030303; KR 20020033665 A 20020507

INPADOC legal status


2010-07-28 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20100202

2002-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020319

2001-05-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010212

2001-05-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI