Global Patent Index - EP 1100464 A1

EP 1100464 A1 20010523 - LIPID EMULSION AND SOLID LIPID NANOPARTICLE AS A GENE OR DRUG CARRIER

Title (en)

LIPID EMULSION AND SOLID LIPID NANOPARTICLE AS A GENE OR DRUG CARRIER

Title (de)

LIPIDEMULSION UND FESTE LIPIDNANOTEILCHEN ALS GEN- ODER WIRKSTOFFCARRIER

Title (fr)

EMULSION LIPIDIQUE ET NANOPARTICULE LIPIDIQUE SOLIDE EN TANT QUE TRANSPORTEURS DE GENES OU DE MEDICAMENTS

Publication

EP 1100464 A1 20010523 (EN)

Application

EP 99935145 A 19990730

Priority

  • KR 9900414 W 19990730
  • KR 19980031249 A 19980731

Abstract (en)

[origin: WO0006120A1] The present invention relates to oil-in-water lipid emulsions composed of non-triglyceride oils and solid lipid nanoparticles (SLN) composed of triglyceride or ethyl stearate used as gene transfection agents and drug delivery systems and method for preparing thereof. The present invention also concerns the method of transferring genes or drugs efficiently into cells by using the lipid emulsions and solid lipid nanoparticles. Also the present invention relates to the method of preparing lipid emulsions containing lipophilic or amphiphilic drugs by using squalene or squalane as the core-oil. The present invention also concerns the method of preparing the solid lipid nanoparticles containing lipophilic or amphiphilic drugs by using ethyl stearate as the core-fat.

IPC 1-7

A61K 9/107

IPC 8 full level

A61K 9/10 (2006.01); A61K 9/107 (2006.01); A61K 9/14 (2006.01); A61K 9/51 (2006.01); A61K 31/196 (2006.01); A61K 31/201 (2006.01); A61K 31/203 (2006.01); A61K 31/5585 (2006.01); A61K 31/566 (2006.01); A61K 31/57 (2006.01); A61K 47/10 (2006.01); A61K 47/14 (2006.01); A61K 47/18 (2006.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61K 47/30 (2006.01); A61K 47/34 (2006.01); A61K 47/42 (2006.01); A61K 47/44 (2006.01); A61K 47/46 (2006.01); A61K 48/00 (2006.01); A61P 31/12 (2006.01); A61P 37/06 (2006.01); C12N 15/88 (2006.01); A61K 9/127 (2006.01)

CPC (source: EP KR)

A61K 9/10 (2013.01 - KR); A61K 9/1075 (2013.01 - EP); A61K 9/5123 (2013.01 - EP); A61K 48/00 (2013.01 - EP); A61P 31/12 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C12N 15/88 (2013.01 - EP); A61K 9/1272 (2013.01 - EP)

Citation (search report)

See references of WO 0006120A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0006120 A1 20000210; AU 5068999 A 20000221; EP 1100464 A1 20010523; JP 2002521423 A 20020716; KR 100374482 B1 20030303; KR 20020033665 A 20020507

DOCDB simple family (application)

KR 9900414 W 19990730; AU 5068999 A 19990730; EP 99935145 A 19990730; JP 2000561977 A 19990730; KR 20020005448 A 20020130