EP 1100521 A4 20021009 - C7F2-A NOVEL POTASSIUM CHANNEL BETA-SUBUNIT

Title (en)

C7F2-A NOVEL POTASSIUM CHANNEL BETA-SUBUNIT

Title (de)

C7F2 - EINE NEUE BETA-UNTEREINHEIT DES KALIUMKANALS

Title (fr)

NOUVELLE SOUS-UNITE BETA DU CANAL A POTASSIUM, C7F2-A

Publication

EP 1100521 A4 20021009 (EN)

Application

EP 99937511 A 19990727

Priority

US 9916949 W 19990727
US 12302098 A 19980727

Abstract (en)

[origin: WO0006183A1] The present invention relates to a newly identified potassium channel beta -subunit. The invention also relates to polynucleotides encoding the subunit. The invention further relates to methods using subunit polypeptides and polynucleotides, applicable to diagnosis and treatment in channel-mediated disorders. The invention further relates to drug-screening methods using the polypeptides and polynucleotides to identify agonists and antagonists, applicable to diagnosis and treatment. The invention further encompasses agonists, and antagonists based on the subunit polypeptides and polynucleotides. The invention further relates to procedures for producing the subunit polypeptides and polynucleotides.

IPC 1-7

A61K 38/00; A61K 48/00; C07K 14/00; C07K 16/00; C12N 15/16; C12N 15/11; C12N 15/63; G01N 33/53

IPC 8 full level

G01N 33/50 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 9/06 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 21/00 (2006.01); A61P 21/02 (2006.01); A61P 25/00 (2006.01); A61P 25/06 (2006.01); A61P 25/08 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/20 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 16/18 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/16 (2006.01); C12P 21/02 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)

CPC (source: EP)

A61P 7/02 (2017.12); A61P 9/00 (2017.12); A61P 9/06 (2017.12); A61P 9/10 (2017.12); A61P 9/12 (2017.12); A61P 21/00 (2017.12); A61P 21/02 (2017.12); A61P 25/00 (2017.12); A61P 25/06 (2017.12); A61P 25/08 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/20 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 43/00 (2017.12); C07K 14/705 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

[E] WO 9942575 A2 19990826 - SANOFI SYNTHELABO [FR], et al
[X] KNAUS HANS-GUNTHER ET AL: "Primary sequence and immunological characterization of beta-subunit of high conductance Ca-2+-activated K+ channel from smooth muscle.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 25, 1994, pages 17274 - 17278, XP002208380, ISSN: 0021-9258 & DATABASE GENBANK [online] 28 September 1994 (1994-09-28), XP002208382, Database accession no. L26101
[X] MAJUMDER KUMUD ET AL: "Molecular cloning and functional expression of a novel potassium channel beta-subunit from human atrium.", FEBS LETTERS, vol. 361, no. 1, 1995, pages 13 - 16, XP002208381, ISSN: 0014-5793
[X] OBERST CORINNA ET AL: "Suppression in transformed avian fibroblasts of a gene (CO6) encoding a membrane protein related to mammalian potassium channel regulatory subunits.", ONCOGENE, vol. 14, no. 9, 1997, pages 1109 - 1116, XP001088992, ISSN: 0950-9232
See references of WO 0006183A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0006183 A1 20000210; AU 5232799 A 20000221; CA 2335643 A1 20000210; EP 1100521 A1 20010523; EP 1100521 A4 20021009; JP 2002524030 A 20020806; MX PA01000952 A 20020820

DOCDB simple family (application)

US 9916949 W 19990727; AU 5232799 A 19990727; CA 2335643 A 19990727; EP 99937511 A 19990727; JP 2000562037 A 19990727; MX PA01000952 A 19990727