Global Patent Index - EP 1100887 A1

EP 1100887 A1 2001-05-23 - GROWTH DIFFERENTIATION FACTOR-11

Title (en)

GROWTH DIFFERENTIATION FACTOR-11

Title (de)

Wachstums-Differenzierungsfaktor 11

Title (fr)

FACTEUR 11 DE DIFFERENTIATION DE CROISSANCE

Publication

EP 1100887 A1 (EN)

Application

EP 99938885 A

Priority

  • US 9917252 W
  • US 12392998 A

Abstract (en)

[origin: WO0006716A1] A transgenic non-human animal of the species selected from the group consisting of avian, bovine, ovine and porcine having a transgene which results in disrupting the production of and/or activity of growth differentiation factor-11 (GDF-11) chromosomally integrated into the germ cells of the animal is disclosed. Also disclosed are methods for making such animals, and methods of treating animals, including humans, with antibodies or antisense directed to GDF-11. The animals so treated are characterized by increased muscle tissue and bone tissue.

IPC 1-7 (main, further and additional classification)

C12N 15/09; C12N 15/63

IPC 8 full level (invention and additional information)

A01K 67/027 (2006.01); A23L 13/00 (2016.01); A61K 31/7088 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 13/12 (2006.01); A61P 19/00 (2006.01); A61P 21/00 (2006.01); C07K 14/475 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01)

CPC (invention and additional information)

C12N 15/8509 (2013.01); A01K 67/0276 (2013.01); C07K 14/475 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A01K 2227/10 (2013.01); A01K 2227/105 (2013.01); A01K 2227/30 (2013.01); A01K 2267/02 (2013.01); A01K 2267/03 (2013.01); A61K 48/00 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0006716 A1 20000210; AU 5327499 A 20000221; AU 765832 B2 20031002; BR 9912548 A 20020129; CA 2336536 A1 20000210; EP 1100887 A1 20010523; EP 1100887 A4 20030115; JP 2002526034 A 20020820; NZ 509609 A 20031128; NZ 528341 A 20050624

INPADOC legal status


2008-03-19 [18R] REFUSED

- Effective date: 20071109

2003-12-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031027

2003-01-15 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20021128

2003-01-15 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2002-08-21 [RIC1] CLASSIFICATION (CORRECTION)

- Free text: 7C 12N 15/09 A, 7C 12N 15/63 B, 7A 01K 67/027 B, 7C 07K 14/51 B

2001-05-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010228

2001-05-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO:

- Free text: AL;LT;LV;MK;RO;SI