EP 1100944 A1 20010523 - TARGETED ALPHAVIRUS AND ALPHAVIRAL VECTORS
Title (en)
TARGETED ALPHAVIRUS AND ALPHAVIRAL VECTORS
Title (de)
ZIELGERICHTETER ALPHAVIRUS UND VEKTOREN DER ALPHAVIRUS
Title (fr)
ALPHAVIRUS CIBLE ET VECTEURS ALPHAVIRAUX
Publication
Application
Priority
- US 9917345 W 19990730
- US 9513898 P 19980730
Abstract (en)
[origin: WO0011201A1] The present invention provides a recombinant alphavirus comprising at least one epiviral nonalphaviral sequence, which (i) is present in the E1, E2 or E3 glycoprotein as an insertion or as a replacement of one or more amino acid residues and which (ii) directly and selectively binds to a region on a target cell-specific, surface receptor. The present invention also provides the nucleic acids related to said alphavirus, and methods to treat cancer in a mammal using the alphavirus and related nucleic acids.
IPC 1-7
C12N 15/86; C12N 15/40; C12N 7/01; C07K 14/18; A61K 39/12; C12Q 1/70
IPC 8 full level
A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/18 (2006.01); C12N 7/00 (2006.01); C12N 15/09 (2006.01); C12N 15/40 (2006.01); C12N 15/86 (2006.01); C12Q 1/02 (2006.01); G01N 33/48 (2006.01); C12R 1/92 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 14/005 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12N 2770/36122 (2013.01); C12N 2770/36143 (2013.01); C12N 2770/36145 (2013.01); C12N 2810/405 (2013.01); C12N 2810/855 (2013.01)
Citation (search report)
See references of WO 0011201A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0011201 A1 20000302; AU 5247199 A 20000314; CA 2337905 A1 20000302; EP 1100944 A1 20010523; IL 141176 A0 20020210; JP 2002523053 A 20020730; ZA 200104382 B 20020828
DOCDB simple family (application)
US 9917345 W 19990730; AU 5247199 A 19990730; CA 2337905 A 19990730; EP 99937686 A 19990730; IL 14117699 A 19990730; JP 2000566453 A 19990730; ZA 200104382 A 20010528