Global patent index - EP 1100944 A1

EP 1100944 A1 2001-05-23 - TARGETED ALPHAVIRUS AND ALPHAVIRAL VECTORS

Title (en)

TARGETED ALPHAVIRUS AND ALPHAVIRAL VECTORS

Title (de)

ZIELGERICHTETER ALPHAVIRUS UND VEKTOREN DER ALPHAVIRUS

Title (fr)

ALPHAVIRUS CIBLE ET VECTEURS ALPHAVIRAUX

Publication

EP 1100944 A1 (EN)

Application

EP 99937686 A

Priority

  • US 9917345 W
  • US 9513898 P

Abstract (en)

[origin: WO0011201A1] The present invention provides a recombinant alphavirus comprising at least one epiviral nonalphaviral sequence, which (i) is present in the E1, E2 or E3 glycoprotein as an insertion or as a replacement of one or more amino acid residues and which (ii) directly and selectively binds to a region on a target cell-specific, surface receptor. The present invention also provides the nucleic acids related to said alphavirus, and methods to treat cancer in a mammal using the alphavirus and related nucleic acids.

IPC 1-7 (main, further and additional classification)

C12N 15/86; A61K 39/12; C07K 14/18; C12N 7/01; C12N 15/40; C12Q 1/70

IPC 8 full level (invention and additional information)

G01N 33/48 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/18 (2006.01); C12N 7/00 (2006.01); C12N 15/09 (2006.01); C12N 15/40 (2006.01); C12N 15/86 (2006.01); C12Q 1/02 (2006.01); C12R 1/92 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12N 2770/36122 (2013.01); C12N 2770/36143 (2013.01); C12N 2770/36145 (2013.01); C12N 2810/405 (2013.01); C12N 2810/855 (2013.01)

Citation (search report)

See references of WO 0011201A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0011201 A1 20000302; AU 5247199 A 20000314; CA 2337905 A1 20000302; EP 1100944 A1 20010523; IL 141176 D0 20020210; JP 2002523053 A 20020730; ZA 200104382 B 20020828

INPADOC legal status

2004-08-25 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040103

2001-05-23 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20010226

2001-05-23 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL;LT;LV;MK;RO;SI