Global Patent Index - EP 1100950 A1

EP 1100950 A1 2001-05-23 - GASTROINTESTINAL BACTERIAL ANTIBODY FACTORIES

Title (en)

GASTROINTESTINAL BACTERIAL ANTIBODY FACTORIES

Title (de)

ANTIKÖRPERFABRIKEN GASTROINTESTINALER BAKTERIEN

Title (fr)

USINES D'ANTICORPS BACTERIENS GASTRO-INTESTINAUX

Publication

EP 1100950 A1 (EN)

Application

EP 99938901 A

Priority

  • US 9917296 W
  • US 9469798 P

Abstract (en)

[origin: WO0006764A1] Neonates during their first thirty days of life are particularly susceptible to pathogens because their immune system is not yet fully functional. Adults may also be unusually susceptible to pathogens when their immune system has been compromised by disease or when they have been acutely exposed to a bolus of GI pathogen. The invention provides a method of immunizing neonates and adults to pathogens by orally administering recombinant probiotic bacteria that express antibodies to the pathogens. These recombinant bacteria may be optionally administered with antibodies immunologically specific to the pathogens. The invention further provides a composition of recombinant probiotic bacteria that express antibodies to pathogen, and a method to use this composition to immunize neonates and adults.

IPC 1-7 (main, further and additional classification)

C12P 21/06; C12N 15/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 35/74 (2006.01); A61K 39/07 (2006.01); A61K 39/108 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 1/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); C07K 16/10 (2006.01); C12N 1/21 (2006.01); C12R 1/225 (2006.01)

CPC (invention and additional information)

C07K 16/10 (2013.01); A61K 2039/505 (2013.01); A61K 2039/542 (2013.01); C07K 2317/622 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 0006764 A1 20000210; AU 5328599 A 20000221; CA 2338001 A1 20000210; EP 1100950 A1 20010523; EP 1100950 A4 20021016; IL 141142 D0 20020210; JP 2002521494 A 20020716

INPADOC legal status


2004-08-04 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040203

2002-10-16 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20020902

2002-10-16 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-23 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010207

2001-05-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-23 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI