Global Patent Index - EP 1102744 A1

EP 1102744 A1 2001-05-30 - NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES

Title (en)

NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON OPTISCH-AKTIVEN ALPHA-AMINONITRILEN

Title (fr)

NOUVEAU PROCEDE DE PREPARATION D'$g(a)-AMINONITRILES OPTIQUEMENT ACTIFS

Publication

EP 1102744 A1 (FR)

Application

EP 00940478 A

Priority

  • FR 0001597 W
  • FR 9907512 A

Abstract (en)

[origin: WO0075104A1] The invention concerns a novel method for preparing optically active alpha -aminonitriles of formula (I) by enantioselective hydrocyanation using a hydrocyanation agent, in the presence of a chiral or chirality inducing metal complex acting as catalyst, of ketimines of formula (II) wherein the radicals R1 and R2 and T are such as defined in the description. The invention also concerns the use of alpha -aminonitriles of formula (I) as synthesis intermediates of optically active organic compounds.

[origin: WO0075104A1] The invention concerns a novel method for preparing optically active alpha -aminonitriles of formula (I) by enantioselective hydrocyanation using a hydrocyanation agent, in the presence of a chiral or chirality inducing metal complex acting as catalyst, of ketimines of formula (II) wherein the radicals R1 and R2 and T are such as defined in the description. The invention also concerns the use of alpha -aminonitriles of formula (I) as synthesis intermediates of optically active organic compounds.

IPC 1-7 (main, further and additional classification)

C07C 253/00; C07D 233/84

IPC 8 full level (invention and additional information)

C07D 233/66 (2006.01); B01J 31/02 (2006.01); C07B 53/00 (2006.01); C07B 61/00 (2006.01); C07C 227/32 (2006.01); C07C 231/06 (2006.01); C07C 231/12 (2006.01); C07C 231/18 (2006.01); C07C 237/20 (2006.01); C07C 253/08 (2006.01); C07C 255/42 (2006.01); C07D 233/84 (2006.01); C07D 317/20 (2006.01)

CPC (invention and additional information)

C07C 231/18 (2013.01); B01J 31/223 (2013.01); B01J 31/226 (2013.01); C07C 227/32 (2013.01); C07C 253/08 (2013.01); C07D 317/20 (2013.01); B01J 2231/322 (2013.01); B01J 2531/0216 (2013.01); B01J 2531/31 (2013.01); B01J 2531/32 (2013.01); B01J 2531/35 (2013.01); B01J 2531/38 (2013.01); B01J 2531/46 (2013.01); B01J 2531/48 (2013.01); B01J 2531/49 (2013.01); B01J 2531/842 (2013.01)

Combination set (CPC)

C07C 253/08 + C07C 255/42

Citation (search report)

See references of WO 0075104A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

FR 2794743 A1 20001215; AU 5540900 A 20001228; BR 0006829 A 20011030; CN 1314880 A 20010926; EP 1102744 A1 20010530; HU 0103428 A2 20020128; JP 2003501411 A 20030114; PL 345995 A1 20020114; TR 200100435 T1 20010821; WO 0075104 A1 20001214

INPADOC legal status


2003-01-08 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020703

2002-04-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020220

2001-05-30 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20010130

2001-05-30 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2001-05-30 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL;LT;LV;MK;RO;SI