EP 1102744 A1 20010530 - NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES

Title (en)

NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON OPTISCH-AKTIVEN ALPHA-AMINONITRILEN

Title (fr)

NOUVEAU PROCEDE DE PREPARATION D'$g(a)-AMINONITRILES OPTIQUEMENT ACTIFS

Publication

EP 1102744 A1 20010530 (FR)

Application

EP 00940478 A 20000609

Priority

FR 0001597 W 20000609
FR 9907512 A 19990609

Abstract (en)

[origin: WO0075104A1] The invention concerns a novel method for preparing optically active alpha -aminonitriles of formula (I) by enantioselective hydrocyanation using a hydrocyanation agent, in the presence of a chiral or chirality inducing metal complex acting as catalyst, of ketimines of formula (II) wherein the radicals R1 and R2 and T are such as defined in the description. The invention also concerns the use of alpha -aminonitriles of formula (I) as synthesis intermediates of optically active organic compounds.

IPC 1-7

C07C 253/00; C07D 233/84

IPC 8 full level

B01J 31/02 (2006.01); C07B 53/00 (2006.01); C07D 233/66 (2006.01); C07B 61/00 (2006.01); C07C 227/32 (2006.01); C07C 231/06 (2006.01); C07C 231/12 (2006.01); C07C 231/18 (2006.01); C07C 237/20 (2006.01); C07C 253/08 (2006.01); C07C 255/42 (2006.01); C07D 233/84 (2006.01); C07D 317/20 (2006.01)

CPC (source: EP KR)

B01J 31/223 (2013.01 - EP); B01J 31/226 (2013.01 - EP); C07C 227/32 (2013.01 - EP); C07C 231/18 (2013.01 - EP); C07C 253/08 (2013.01 - EP); C07C 255/24 (2013.01 - KR); C07D 317/20 (2013.01 - EP); B01J 2231/322 (2013.01 - EP); B01J 2531/0216 (2013.01 - EP); B01J 2531/31 (2013.01 - EP); B01J 2531/32 (2013.01 - EP); B01J 2531/35 (2013.01 - EP); B01J 2531/38 (2013.01 - EP); B01J 2531/46 (2013.01 - EP); B01J 2531/48 (2013.01 - EP); B01J 2531/49 (2013.01 - EP); B01J 2531/842 (2013.01 - EP)

C-Set (source: EP)

C07C 253/08 + C07C 255/42

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0075104 A1 20001214; AU 5540900 A 20001228; BR 0006829 A 20011030; CN 1314880 A 20010926; EP 1102744 A1 20010530; FR 2794743 A1 20001215; HU P0103428 A2 20020128; JP 2003501411 A 20030114; KR 20010072385 A 20010731; PL 345995 A1 20020114; TR 200100435 T1 20010821

DOCDB simple family (application)

FR 0001597 W 20000609; AU 5540900 A 20000609; BR 0006829 A 20000609; CN 00801171 A 20000609; EP 00940478 A 20000609; FR 9907512 A 19990609; HU P0103428 A 20000609; JP 2001501585 A 20000609; KR 20017001744 A 20010209; PL 34599500 A 20000609; TR 200100435 T 20000609