EP 1102784 A1 20010530 - A COMPOUND CONTAINING A LABILE DISULFIDE BOND
Title (en)
A COMPOUND CONTAINING A LABILE DISULFIDE BOND
Title (de)
EINE VERBINDUNG MIT EINER LABILEN DISULFID-BINDUNG
Title (fr)
COMPOSE CONTENANT UNE LIAISON INSTABLE DE BISULFURE
Publication
Application
Priority
- US 0015652 W 20000607
- US 13785999 P 19990607
Abstract (en)
[origin: WO0075162A1] A labile disulfide-containing compound under physiological conditions, comprising: the disulfide-containing compound having a labile disulfide bond that is either a disulfide bond that is cleaved more rapidly than oxidized glutathione or a disulfide bond constructed from thiols in which one of the constituent thiols has a lower pKa than glutathione or a disulfide bond that is activated by intramolecular attack from a free thiol.
IPC 1-7
IPC 8 full level
A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); C07C 323/52 (2006.01); C07C 323/62 (2006.01); C07H 21/00 (2006.01); C07K 7/06 (2006.01); C12N 15/87 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); C07C 323/60 (2013.01); C07D 207/40 (2013.01); C07D 403/12 (2013.01); C07H 21/00 (2013.01); C07K 7/06 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0075162 A1 20001214; EP 1102784 A1 20010530; EP 1102784 A4 20091230; JP 2003501440 A 20030114
DOCDB simple family (application)
US 0015652 W 20000607; EP 00939635 A 20000607; JP 2001502443 A 20000607