EP 1105153 A1 20010613 - MULTIVALENT VACCINE FOR (CLOSTRIDIUM BOTULINUM) NEUROTOXIN
Title (en)
MULTIVALENT VACCINE FOR (CLOSTRIDIUM BOTULINUM) NEUROTOXIN
Title (de)
MULTIVALENTER IMPFSTOFF GEGEN CLOSTRIDIUM BOTULINUM NEUTOTOXIN
Title (fr)
VACCIN POLYVALENT CONTRE LA NEUROTOXINE DU (CLOSTRIDIUM BOTILINUM)
Publication
Application
Priority
- US 9715394 W 19970828
- US 70415996 A 19960828
Abstract (en)
[origin: WO9808540A1] The present invention includes recombinant proteins derived from Clostridium botulinum toxins. In particular, soluble recombinant Clostridium botulinum type A, type B and type E toxin proteins are provided. Methods which allow for the isolation of recombinant proteins free of significant endotoxin contamination are provided. The soluble, endotoxin-free recombinant proteins are used as immunogens for the production of vaccines and antitoxins. These vaccines and antitoxins are useful in the treatment of humans and other animals at risk of intoxication with clostridial toxin.
IPC 1-7
A61K 39/00; A61K 39/38; A61K 38/08; C12P 21/06; C12P 21/04; C12P 21/08; C12N 15/00; C12N 15/09; C12N 15/63; C12N 15/70; C12N 15/74; C07K 16/02
IPC 8 full level
C07K 14/33 (2006.01); C07K 16/02 (2006.01); C07K 16/12 (2006.01); C12P 21/04 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
C07K 14/33 (2013.01); C07K 16/02 (2013.01); C07K 16/1282 (2013.01); A61K 39/00 (2013.01); Y02A 50/30 (2018.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9808540 A1 19980305; AU 4245097 A 19980319; CA 2296765 A1 19980305; EP 1105153 A1 20010613; EP 1105153 A4 20050119
DOCDB simple family (application)
US 9715394 W 19970828; AU 4245097 A 19970828; CA 2296765 A 19970828; EP 97940746 A 19970828