EP 1105425 A1 20010613 - MONOCLONAL ANTIBODIES SPECIFIC FOR STREPTOCOCCUS MUTANS, AND USES THEREOF
Title (en)
MONOCLONAL ANTIBODIES SPECIFIC FOR STREPTOCOCCUS MUTANS, AND USES THEREOF
Title (de)
MONOKLONALE ANTIKÖRPER SPEZIFISCH FÜR STREPTOCOCCUS MUTANS, UND DEREN VERWENDUNGEN
Title (fr)
ANTICORPS MONOCLONAUX SPECIFIQUES DE $i(STREPTOCOCCUS MUTANS) ET LEURS UTILISATIONS
Publication
Application
Priority
- US 9919034 W 19990820
- US 9747098 P 19980821
- US 10217998 P 19980928
Abstract (en)
[origin: WO0011037A1] The invention describes three monoclonal IgG antibodies, referred to as SWLA1, SWLA2, and SWLA3, which appear to recognize a species-specific lipooligosaccharide or lipopolysaccharide on the cell surface of S.mutans. The invention also describes a rapid method of detection of S.mutans without the need for prior growth of the bacteria in culture. The invention further describes method of utilizing these antibodies for rapidly quantitatively detecting S.mutans. These methods are sensitive enough to detect the presence of a single S.mutans bacterial cell. These methods can be widely used in the clinical diagnosis and treatment of dental caries in humans.
IPC 1-7
IPC 8 full level
G01N 33/569 (2006.01); C07K 16/12 (2006.01); C12N 5/10 (2006.01); C12P 21/08 (2006.01); G01N 33/577 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 16/1275 (2013.01)
Citation (search report)
See references of WO 0011037A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0011037 A1 20000302; AU 5576399 A 20000314; AU 756242 B2 20030109; EP 1105425 A1 20010613; JP 2002523427 A 20020730; JP 4731687 B2 20110727
DOCDB simple family (application)
US 9919034 W 19990820; AU 5576399 A 19990820; EP 99942369 A 19990820; JP 2000566309 A 19990820