EP 1105733 A1 20010613 - RECEPTOR FOR UNDERIVATIZED, AQUEOUS SOLUBLE BETA-(1,3)-GLUCAN
Title (en)
RECEPTOR FOR UNDERIVATIZED, AQUEOUS SOLUBLE BETA-(1,3)-GLUCAN
Title (de)
REZEPTOR FÜR NICHT-DERIVATISIERTES, WASSER-LÖSLICHES BETA-(1,3)-GLUCAN
Title (fr)
RECEPTEUR POUR BETA-(1,3)-GLUCANE NON DERIVE, SOLUBLE DANS L'EAU
Publication
Application
Priority
- US 9918995 W 19990819
- US 14019698 A 19980826
- US 16092298 A 19980925
Abstract (en)
[origin: WO0013019A1] Methods of isolating beta (1,3)-glucan or beta (1,3)-glucan-containing organisms in a sample, or of detecting the presence of beta (1,3)-glucan or beta (1,3)-glucan-containing organisms in a sample, utilizing a proteinaceous receptor for underivatized, aqueous soluble beta (1,3)-glucan (e.g., an NR8383 receptor) are described. Methods of diagnosing fungal infection, by detecting beta (1,3)-glucan or beta (1,3)-glucan-containing organisms, are also described. Antibodies and kits useful in the methods are also disclosed. A preparation containing a proteinaceous receptor for underivatized, aqueous soluble beta (1,3)-glucan is additionally disclosed, along with characterization of the receptor for underivatized, aqueous soluble beta (1,3)-glucan. Also described are assays for identifying agents which alter the effect of underivatized, aqueous soluble beta (1,3)-glucan on activation of signal transduction pathways and agents identified thereby.
IPC 1-7
IPC 8 full level
C07K 1/22 (2006.01); C07K 14/00 (2006.01); G01N 33/53 (2006.01)
CPC (source: EP)
G01N 33/5308 (2013.01)
Citation (search report)
See references of WO 0013019A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0013019 A1 20000309; WO 0013019 A9 20010322; AU 5681999 A 20000321; AU 749716 B2 20020704; CA 2341668 A1 20000309; EP 1105733 A1 20010613; JP 2002523522 A 20020730; JP 2011102323 A 20110526; MX PA01002022 A 20020424
DOCDB simple family (application)
US 9918995 W 19990819; AU 5681999 A 19990819; CA 2341668 A 19990819; EP 99943790 A 19990819; JP 2000567952 A 19990819; JP 2011011128 A 20110121; MX PA01002022 A 19990819