EP 1105734 A2 20010613 - HOMER INTERACTING PROTEINS
Title (en)
HOMER INTERACTING PROTEINS
Title (de)
MIT 'HOMER' INTERAGIERENDE PROTEINE
Title (fr)
PROTEINES A INTERACTION DE LA FAMILLE HOMER
Publication
Application
Priority
- US 9918973 W 19990818
- US 9733498 P 19980818
- US 13849399 P 19990609
- US 13842699 P 19990609
- US 13849499 P 19990609
Abstract (en)
[origin: WO0011204A2] A method is provided for identifying a compound that modulates a cellular response associated with Homer and mediated by a cell-surface or an intracellular receptor. A method is further provided for identifying a compound that modulates receptor activated calcium mobilization associated with Homer. A method is provided for identifying a compound that inhibits Homer protein activity based on the crystal structure coordinates of Homer protein binding domain. A method is also provided for identifying a compound that affects the formation of cell surface receptors into clusters. Also provided are nucleic acids encoding Homer proteins as well as Homer proteins, and Homer interacting proteins.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 45/00 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); A61P 15/00 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 25/08 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); A61P 39/02 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 13/12 (2017.12); A61P 15/00 (2017.12); A61P 21/00 (2017.12); A61P 25/00 (2017.12); A61P 25/08 (2017.12); A61P 25/18 (2017.12); A61P 25/28 (2017.12); A61P 39/02 (2017.12); C07K 14/47 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0011204 A2 20000302; WO 0011204 A3 20010215; AU 5779899 A 20000314; AU 772105 B2 20040408; EP 1105734 A2 20010613; EP 1105734 A4 20050413; JP 2002523056 A 20020730
DOCDB simple family (application)
US 9918973 W 19990818; AU 5779899 A 19990818; EP 99945113 A 19990818; JP 2000566456 A 19990818