EP 1108051 A2 20010620 - INDUCIBLE EXPRESSION SYSTEM
Title (en)
INDUCIBLE EXPRESSION SYSTEM
Title (de)
INDUZIERBARES EXPRESIONSSYSTEM
Title (fr)
SYSTEME D'EXPRESSION INDUCTIBLE
Publication
Application
Priority
- FR 9902051 W 19990827
- FR 9810842 A 19980828
Abstract (en)
[origin: FR2782732A1] The invention concerns an inducible expression system using nucleotide sequences coding for a transcriptional activator of eukaryotic or viral origin and a recombinant adenoviral vector comprising a gene of interest placed under the control of a promoter inducible in trans by said transcriptional activator. The invention also concerns a recombinant adenoviral vector bearing a first expression cassette coding for a transcriptional activator and a second cassette bearing a gene of interest placed under the control of a promoter inducible in trans by said transcriptional activator. The invention further concerns an infectious viral particle, its preparation method, a eukaryotic cell and a pharmaceutical composition comprising such a vector or expression system as well as their use for therapeutic or prophylactic purposes.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2015.01); A61K 35/761 (2015.01); A61K 35/763 (2015.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); A61P 7/04 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12N 15/861 (2006.01)
CPC (source: EP)
A61P 3/10 (2017.12); A61P 7/04 (2017.12); A61P 9/00 (2017.12); A61P 9/08 (2017.12); A61P 31/00 (2017.12); A61P 31/04 (2017.12); A61P 31/12 (2017.12); A61P 31/18 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/00 (2013.01); C12N 2830/15 (2013.01)
Citation (search report)
See references of WO 0012741A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
FR 2782732 A1 20000303; AU 5426299 A 20000321; CA 2341775 A1 20000309; EP 1108051 A2 20010620; JP 2002523106 A 20020730; WO 0012741 A2 20000309; WO 0012741 A3 20000504; WO 0012741 A9 20010329
DOCDB simple family (application)
FR 9810842 A 19980828; AU 5426299 A 19990827; CA 2341775 A 19990827; EP 99940240 A 19990827; FR 9902051 W 19990827; JP 2000567726 A 19990827