Global Patent Index - EP 1108053 A1

EP 1108053 A1 20010620 - METHOD FOR PREPARING (2R)-PIPERIDINE DERIVATIVES

Title (en)

METHOD FOR PREPARING (2R)-PIPERIDINE DERIVATIVES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON (2R)-PIPERIDINDERIVATEN

Title (fr)

PROCEDE DE PREPARATION DE DERIVES DE (2R)-PIPERIDINE

Publication

EP 1108053 A1 20010620 (DE)

Application

EP 99944524 A 19990826

Priority

  • EP 99944524 A 19990826
  • EP 9906277 W 19990826
  • EP 98116061 A 19980826

Abstract (en)

[origin: WO0012745A1] The invention relates to a method for preparing (R)-piperidine derivatives of the general formulas (I) and (VII), where R<1> is hydroxy, amino or C1-6-alkoxy and R<4> is hydroxy or amino. Said (R)-piperidine derivatives are obtained from (RS)-piperidine derivatives of the general formula (II), in which R<2> is hydroxy, amino or C1-6-alkoxy, in the presence of trace elements and using micro-organisms or cell-free enzymes from said micro-organisms.

IPC 1-7

C12P 17/12; C07D 211/60; C07D 211/22; C07D 211/26

IPC 8 full level

C07D 211/22 (2006.01); C07D 211/26 (2006.01); C07D 211/60 (2006.01); C12P 17/12 (2006.01); C12P 41/00 (2006.01); C12R 1/40 (2006.01)

CPC (source: EP)

C07D 211/22 (2013.01); C07D 211/26 (2013.01); C07D 211/60 (2013.01); C12P 17/12 (2013.01); C12P 41/001 (2013.01)

Citation (search report)

See references of WO 0012745A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0012745 A1 20000309; AU 5741599 A 20000321; CA 2341554 A1 20000309; EP 1108053 A1 20010620; JP 2002523107 A 20020730

DOCDB simple family (application)

EP 9906277 W 19990826; AU 5741599 A 19990826; CA 2341554 A 19990826; EP 99944524 A 19990826; JP 2000567728 A 19990826