Global Patent Index - EP 1112271 A1

EP 1112271 A1 20010704 - ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT

Title (en)

ERGOLINE AMINE DERIVATIVES WITH BLOOD PRESSURE LOWERING EFFECT

Title (de)

ERGOLINAMIN-DERIVATE MIT BLUTDRUCKSENKENDER WIRKUNG

Title (fr)

DERIVES D'ERGOLINAMINE A EFFET HYPOTENSEUR

Publication

EP 1112271 A1 20010704 (DE)

Application

EP 99961974 A 19990715

Priority

  • DE 9902194 W 19990715
  • DE 19832191 A 19980717

Abstract (en)

[origin: DE19832191A1] N-Acylated aminomethyl-ergoline derivatives (I) are new. N-Acylated aminomethyl-ergoline derivatives of formula (I) and their salts are new. R5 = H, alkyl, aryl, acyl or CN; R6 = H, alkyl or halo; R7, R8 = H or together form a bond; R1 = residue of a diamine; R4 = residue of a dicarboxylic acid; R2 = H or acyl; R3 = H; or R2, R3 = residue of a diamine.

IPC 1-7

C07D 457/02; C07F 17/02; C07F 15/02; A61K 31/48; A61K 33/26

IPC 8 full level

A61K 31/48 (2006.01); A61K 33/26 (2006.01); A61P 9/00 (2006.01); A61P 9/12 (2006.01); C07D 457/02 (2006.01); C07F 15/02 (2006.01); C07F 17/02 (2006.01)

CPC (source: EP US)

A61P 9/00 (2017.12 - EP); A61P 9/12 (2017.12 - EP); C07D 457/02 (2013.01 - EP US); C07F 15/025 (2013.01 - EP US); C07F 17/02 (2013.01 - EP US)

Citation (search report)

See references of WO 0004018A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

DE 19832191 A1 20000127; CA 2337881 A1 20000127; EP 1112271 A1 20010704; JP 2002520411 A 20020709; US 6358967 B1 20020319; WO 0004018 A1 20000127

DOCDB simple family (application)

DE 19832191 A 19980717; CA 2337881 A 19990715; DE 9902194 W 19990715; EP 99961974 A 19990715; JP 2000560124 A 19990715; US 74386901 A 20010419