EP 1112365 A2 20010704 - HUMAN AND MURINE G-PROTEIN-COUPLED EDG6 RECEPTOR (ENDOTHELIAL DIFFERENTIATION GENE) AND USE OF SAME
Title (en)
HUMAN AND MURINE G-PROTEIN-COUPLED EDG6 RECEPTOR (ENDOTHELIAL DIFFERENTIATION GENE) AND USE OF SAME
Title (de)
HUMANER UN MURINER G-PROTEIN GEKOPPELTER REZEPTOR EDG6 (ENDOTHELIAL DIFFERENTIATION GEN) UND SEINE VERWENDUNG
Title (fr)
RECEPTEUR EDG6 (GENE DE DIFFERENTIATION DE CELLULES ENDOTHELIALES) HUMAIN ET MURIN COUPLE A DES PROTEINES G ET SON UTILISATION
Publication
Application
Priority
- DE 9902871 W 19990910
- DE 19843240 A 19980911
- DE 19846979 A 19981013
Abstract (en)
[origin: WO0015784A2] The invention relates to the G protein-coupled EDG6 receptor, fragments, variants and mutations thereof, as well as to its use. Areas of application of the invention include molecular biology, pharmacy and medicine. The aim of the invention is to isolate and identify a further member of the family of EDG receptors and to permit its use for medical purposes. The new human EDG6 receptor comprises 384 amino acids of sequence 1 having seven transmembrane domains. The receptor has a possible N-terminal glycolysis site, three possible palmitoylation sites, between 12 and 15 amino acids in the C-terminal position of the seventh transmembrane domain and four possible C-terminal proteinkinase C-phosphorylation sites. The invention further relates to the use of the EDG6 receptor, its fragments, variants and mutations and possibly its binding partners for therapeutic methods and treatments.
IPC 1-7
C12N 15/12; C07K 14/705; C07K 16/28; G01N 33/68; A61K 38/17; A01K 67/027; A61K 49/00
IPC 8 full level
A01K 67/027 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01); G01N 33/577 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 29/00 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07K 14/705 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 0015784A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0015784 A2 20000323; WO 0015784 A3 20000817; EP 1112365 A2 20010704; JP 2002525050 A 20020813
DOCDB simple family (application)
DE 9902871 W 19990910; EP 99948712 A 19990910; JP 2000570311 A 19990910