EP 1113803 A1 20010711 - ANTIVIRAL COMBINATIONS COMPRISING LAMIVUDINE AND ABACAVIR
Title (en)
ANTIVIRAL COMBINATIONS COMPRISING LAMIVUDINE AND ABACAVIR
Title (de)
ANTIVIRALE KOMBINATION ENTHALTEND LAMIVUDIN UND ABACAVIR
Title (fr)
COMBINAISONS ANTIVIRALES CONTENANT DE LA LAMIVUDINE ET DE L'ABACAVIR
Publication
Application
Priority
- EP 9906885 W 19990917
- GB 9820417 A 19980918
Abstract (en)
[origin: WO0016779A1] The present invention relates to therapeutic combinations comprising (2R,cis) -4-amino -1-(2-hydroxymethyl -1,3-oxathiolan -5-yl) -pyrimidin -2-one (lamivudine) and (-)-(1S, 4R)-4-[2 -amino-6 -(cyc lopropylamino) -9H-purin -9-yl] -2-cyclopentene -1-methanol (1592U89, abacavir). The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HBV infections including infections with HBV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors of the replication of the hepatitis B virus.
IPC 1-7
IPC 8 full level
A61K 9/00 (2006.01); A61K 31/506 (2006.01); A61K 31/52 (2006.01); A61P 1/16 (2006.01); A61P 31/12 (2006.01)
CPC (source: EP KR)
A61K 31/513 (2013.01 - KR); A61K 31/52 (2013.01 - EP); A61P 1/16 (2017.12 - EP); A61P 31/12 (2017.12 - EP)
Citation (search report)
See references of WO 0016779A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0016779 A1 20000330; AU 6085099 A 20000410; CN 1317971 A 20011017; EP 1113803 A1 20010711; GB 9820417 D0 19981111; JP 2002526449 A 20020820; KR 20010075202 A 20010809
DOCDB simple family (application)
EP 9906885 W 19990917; AU 6085099 A 19990917; CN 99811006 A 19990917; EP 99947375 A 19990917; GB 9820417 A 19980918; JP 2000573740 A 19990917; KR 20017003499 A 20010317