Global Patent Index - EP 1114157 A2

EP 1114157 A2 20010711 - REGULATORY PROTEIN FROM HUMAN KERATINOCYTES

Title (en)

REGULATORY PROTEIN FROM HUMAN KERATINOCYTES

Title (de)

REGULATORISCHES PROTEIN AUS HUMANEN KERATINOZYTEN

Title (fr)

PROTEINE REGULATRICE ISSUE DE KERATINOCYTES HUMAINS

Publication

EP 1114157 A2 20010711 (DE)

Application

EP 99969420 A 19990906

Priority

  • DE 9902865 W 19990906
  • DE 19842863 A 19980919

Abstract (en)

[origin: WO0017232A2] The invention relates to an isolated polypeptide which is equivalent to or similar (i.e., equivalent in function and effect) to a protein which is naturally occurring in human keratinocytes and which is increasingly expressed in the activated state of the keratinocytes. The invention also relates to an isolated nucleic acid encoding such a polypeptide or protein typical of human keratinocytes, as well as to the use of said polypeptide and said nucleic acid for the purpose of assays, particularly for diagnostic purposes, and/or for therapeutic purposes, or to the use of reagents, particularly of recombinant vector molecules and antibodies directed against such molecules. The inventive protein has an amino acid sequence of SEQ ID NO:2 or SEQ ID NO:3 of the sequence listing or an allele or derivative of said amino acid sequence derivedy amino acid substitution, deletion, insertion or inversion. The inventive nucleic acid has a nucleotide sequence as depicted in SEQ ID NO:1 or SEQ ID NO:4 of the sequence listing or a nucleotide sequence complementary thereto or a partial sequence of one of these nucleotide sequences or a nucleotide sequence which fully or partially hybridizes to any of the above-mentioned nucleotide sequences.

IPC 1-7

C12N 15/12; C12N 15/11; C12N 15/85; C12N 5/10; C07K 14/47; C07K 16/18; A61K 38/17; A61K 39/395; G01N 33/53

IPC 8 full level

A01K 67/027 (2006.01); A61K 31/711 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 17/00 (2006.01); C07K 14/47 (2006.01); C07K 16/40 (2006.01); C12N 5/10 (2006.01); C12N 9/12 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01)

CPC (source: EP)

A61P 17/00 (2017.12); C07K 14/47 (2013.01)

Citation (search report)

See references of WO 0017232A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 0017232 A2 20000330; WO 0017232 A3 20001012; AU 1149100 A 20000410; CA 2342957 A1 20000330; DE 19842863 A1 20000427; DE 19981873 D2 20020124; EP 1114157 A2 20010711; JP 2002526060 A 20020820

DOCDB simple family (application)

DE 9902865 W 19990906; AU 1149100 A 19990906; CA 2342957 A 19990906; DE 19842863 A 19980919; DE 19981873 T 19990906; EP 99969420 A 19990906; JP 2000574140 A 19990906