EP 1115419 A2 20010718 - CARBAPENEM ANTIBACTERIAL COMPOSITIONS AND METHODS OF TREATMENT
Title (en)
CARBAPENEM ANTIBACTERIAL COMPOSITIONS AND METHODS OF TREATMENT
Title (de)
CARBAPENEM-ENTHALTENDE ANTIBAKTERIELLE ZUSAMMENSETZUNGEN UND DAMIT ZUSAMMENHÄNGENDES BEHANDLUNGSVERFAHREN
Title (fr)
COMPOSITIONS ANTIBACTERIENNES CARBAPENEMS ET METHODES DE TRAITEMENT ASSOCIEES
Publication
Application
Priority
- US 9920052 W 19990831
- US 9873898 P 19980901
Abstract (en)
[origin: WO0012048A2] The present invention relates to novel 2-(naphthosultamyl)methyl-carbapenem antibacterial agents or pharmaceutically acceptable salts thereof in combination with other beta -lactams, which are useful in treating and preventing enterococcal infections. The combinations have anti-PBP5 activity as well as activity against the critical PBPs of sensitive isolates. The antibacterial compositions of the present invention thus comprise an important contribution to therapy for treating infections caused by these difficult to control pathogens. This combination is also useful against gram positive microorganisms, especially methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS).
IPC 1-7
A61K 38/16; A61K 31/65; A61K 31/43; A61K 31/545; A61K 31/47; A61K 31/42
IPC 8 full level
C07D 477/00 (2006.01); A61K 31/164 (2006.01); A61K 31/397 (2006.01); A61K 31/429 (2006.01); A61K 31/437 (2006.01); A61K 31/47 (2006.01); A61K 31/545 (2006.01); A61K 31/7052 (2006.01); A61K 31/726 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01)
CPC (source: EP)
A61K 45/06 (2013.01); A61P 31/04 (2017.12)
Citation (search report)
See references of WO 0012048A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0012048 A2 20000309; WO 0012048 A3 20000622; AU 6133599 A 20000321; CA 2341650 A1 20000309; EP 1115419 A2 20010718; JP 2002525275 A 20020813
DOCDB simple family (application)
US 9920052 W 19990831; AU 6133599 A 19990831; CA 2341650 A 19990831; EP 99948094 A 19990831; JP 2000571020 A 19990831