EP 1117651 A1 20010725 - NEW BIS-BENZIMIDAZOLES
Title (en)
NEW BIS-BENZIMIDAZOLES
Title (de)
BIS-BENZIMIDAZOLE DERIVATE
Title (fr)
NOUVEAUX BIS-BENZIMIDAZOLES
Publication
Application
Priority
- JP 9905319 W 19990929
- US 10271198 P 19981001
- US 11726999 P 19990126
- US 12327799 P 19990309
Abstract (en)
[origin: WO0020401A1] Bis-benzimidazole compounds of general formula (I) in which R<1>, R<2>, R<3> and R<4> are hydrogen, hydroxy or halogen, R<5> and R<8> are hydrogen, or (C1-C4)-alkyl,R<6> and R<7> are hydrogen, or (C1-C6)-alkyl, hydroxy, halogen, or (C1-C6)-alkoxy, R<9>, R<10> and R<11> are hydrogen, halogen, nitro, cyano or trifluoromethyl, and A is a non-aromatic 5-7-membered N-heterocycle, etc, process for their preparation and their use for treating diseases associated with tryptase activity including allergic, inflammatory and related immunological diseases, in particular asthma, allergic rhinitis, allergic conjunctivitis and allergic dermatitis.
IPC 1-7
C07D 235/20; C07D 403/14; C07D 401/14; C07D 471/04; A61K 31/4184; A61K 31/437
IPC 8 full level
A61K 31/4184 (2006.01); A61K 31/437 (2006.01); A61K 31/4427 (2006.01); A61K 31/454 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/551 (2006.01); A61P 11/06 (2006.01); A61P 27/14 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 235/20 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 27/14 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12); C07D 235/20 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01)
Citation (search report)
See references of WO 0020401A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0020401 A1 20000413; AR 021838 A1 20020807; AU 5998199 A 20000426; CA 2346040 A1 20000413; CO 5261509 A1 20030331; EP 1117651 A1 20010725; GT 199900167 A 20010321; JP 2002526537 A 20020820; PE 20001057 A1 20010103
DOCDB simple family (application)
JP 9905319 W 19990929; AR P990104911 A 19990929; AU 5998199 A 19990929; CA 2346040 A 19990929; CO 99062024 A 19990930; EP 99969935 A 19990929; GT 199900167 A 19990928; JP 2000574518 A 19990929; PE 00098699 A 19990929