EP 1119584 A1 20010801 - PEPTIDES RELATED TO AN IGF-II-R EPITOPE, POLYNUCLEOTIDES ENCODING THE PEPTIDES, AND THEIR USE IN IMMUNOMODULATION
Title (en)
PEPTIDES RELATED TO AN IGF-II-R EPITOPE, POLYNUCLEOTIDES ENCODING THE PEPTIDES, AND THEIR USE IN IMMUNOMODULATION
Title (de)
VON EINEM IGF-II-R EPITOP ABGELEITETE PEPTIDE, KODIERENDE POLYNUKLEOTIDE, UND IHRE ANWENDUNG ZUR IMMUNOMODULATION
Title (fr)
PEPTIDES APPARENTES A UN EPITOPE IGF-II-R, POLYNUCLEOTIDES CODANT CES PEPTIDES, ET UTILISATION DE CEUX-CI DANS L'IMMUNOMODULATION
Publication
Application
Priority
- US 9923167 W 19991004
- US 10322998 P 19981005
- US 11481199 P 19990105
- US 12000199 P 19990211
- US 12000299 P 19990211
Abstract (en)
[origin: WO0020457A1] The present invention provides novel synthetic antigenic peptide epitopes, related to IGF-II-R. These synthetic antigenic peptide epitopes are designed for enhanced binding to MHC molecules, and have enhanced immunoregulatory properties relative to their natural counterparts. The synthetic antigenic peptide epitopes of the invention are useful in a variety of methods of modulating an immune response to the synthetic antigenic peptide epitopes and thus to the corresponding native antigenic determinant. Synthetic antigenic peptide epitopes of the invention thus find application in a wide variety of immunomodulatory protocols, including methods to induce or increase an immune response, as well as in methods to suppress or reduce an undesirable immune response, to a corresponding natural epitope.
IPC 1-7
IPC 8 full level
A61K 35/12 (2006.01); A61K 35/14 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); G01N 33/53 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/62 (2006.01); C12N 15/67 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP US)
A61K 40/00 (2025.01 - EP US); A61K 40/19 (2025.01 - EP US); A61K 40/24 (2025.01 - EP US); A61K 40/4203 (2025.01 - EP US); A61K 40/4273 (2025.01 - EP US); A61K 45/06 (2013.01 - EP); A61P 35/00 (2018.01 - EP); C07K 14/47 (2013.01 - EP); C07K 14/4748 (2013.01 - EP); C07K 14/72 (2013.01 - EP); C12N 15/62 (2013.01 - EP); C12N 15/67 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP US); A61K 2239/31 (2023.05 - EP US); A61K 2239/38 (2023.05 - EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0020457 A1 20000413; AU 1102100 A 20000426; AU 767391 B2 20031106; CA 2345477 A1 20000413; EP 1119584 A1 20010801; JP 2002526102 A 20020820
DOCDB simple family (application)
US 9923167 W 19991004; AU 1102100 A 19991004; CA 2345477 A 19991004; EP 99954742 A 19991004; JP 2000574568 A 19991004