EP 1121154 A2 20010808 - MACROMOLECULAR ACTIVE SUBSTANCE CONJUGATES AND A METHOD FOR THE PRODUCTION THEREOF
Title (en)
MACROMOLECULAR ACTIVE SUBSTANCE CONJUGATES AND A METHOD FOR THE PRODUCTION THEREOF
Title (de)
MAKROMOLEKULARE WIRKSTOFFKONJUGATE UND VERFAHREN ZU IHRER HERSTELLUNG
Title (fr)
CONJUGUES MACROMOLECULAIRES DE SUBSTANCES ACTIVES ET TECHNIQUE DE PRODUCTION ASSOCIEE
Publication
Application
Priority
- DE 9903338 W 19991014
- DE 19847362 A 19981014
Abstract (en)
[origin: DE19847362A1] A novel conjugate (I) comprises a polycyclic, planar aromatic compound (II) and a protein (III) not regarded as foreign by the body. An Independent claim is included for the preparation of (I), by dissolving (II) in a polar organic solvent and coupling with (III) using a bifunctional acid chloride (preferably thionyl chloride or thiophosgene).
IPC 1-7
IPC 8 full level
A61K 47/48 (2006.01); C07K 14/765 (2006.01); C07K 14/79 (2006.01); A61K 38/00 (2006.01); A61K 47/02 (2006.01)
CPC (source: EP)
A61K 47/643 (2017.07); C07K 14/765 (2013.01); C07K 14/79 (2013.01); A61K 38/00 (2013.01); A61K 47/02 (2013.01); Y02A 50/30 (2017.12)
Citation (search report)
See references of WO 0021569A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
DE 19847362 A1 20000420; AU 1768200 A 20000501; EP 1121154 A2 20010808; WO 0021569 A2 20000420; WO 0021569 A3 20000824
DOCDB simple family (application)
DE 19847362 A 19981014; AU 1768200 A 19991014; DE 9903338 W 19991014; EP 99960791 A 19991014