EP 1121462 A2 20010808 - GENES FOR ASSESSING CARDIOVASCULAR STATUS AND COMPOSITIONS FOR USE THEREOF
Title (en)
GENES FOR ASSESSING CARDIOVASCULAR STATUS AND COMPOSITIONS FOR USE THEREOF
Title (de)
GENE ZUR FESTSTELLUNG DES KARDIOVASKULÄREN ZUSTANDES UND ZUSAMMENSETZUNGEN ZU DEREN BENUTZUNG
Title (fr)
GENES D'EVALUATION D'ETAT CARDIO-VASCULAIRE ET COMPOSITIONS D'UTILISATIONS ASSOCIEES
Publication
Application
Priority
- IB 9901678 W 19991013
- US 10428698 P 19981014
- US 10430298 P 19981014
Abstract (en)
[origin: WO0022166A2] The present invention provides methods for assessing cardiovascular status in an individual, which comprise determining the sequence at one or more polymorphic positions within the human genes encoding ACE, AT1, AGT, renin, aldosterone synthase, type-2 angiotensin II receptor, endothelin receptor, and beta -adrenoceptor. The invention also provides isolated nucleic acids encoding polymorphisms in genes encoding ACE, AT1, AGT, renin, aldosterone synthase, type-2 angiotensin II receptor, endothelin receptor and beta -adrenoceptor, nucleic acid probes that hybridized to polymorphic positions, kits for the prediction of cardiovascular status, and nucleic acid and peptide targets for use in identifying candidate cardiovascular drugs.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12N 9/02 (2006.01); C12N 9/64 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
C07K 14/70571 (2013.01); C07K 14/72 (2013.01); C12N 9/0079 (2013.01); C12N 9/6486 (2013.01); C12Q 1/6883 (2013.01); C12Y 304/23015 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01)
Citation (search report)
See references of WO 0022166A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0022166 A2 20000420; WO 0022166 A3 20000914; AU 6116399 A 20000501; CA 2347247 A1 20000420; EP 1121462 A2 20010808; IL 142548 A0 20020310; JP 2002527079 A 20020827; NO 20011847 D0 20010410; NO 20011847 L 20010614
DOCDB simple family (application)
IB 9901678 W 19991013; AU 6116399 A 19991013; CA 2347247 A 19991013; EP 99947799 A 19991013; IL 14254899 A 19991013; JP 2000576056 A 19991013; NO 20011847 A 20010410