EP 1124802 A1 20010822 - PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS
Title (en)
PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON 4-ARYLPIPERIDIN-3-CARBINOLEN UND VERWANDTE VERBINDUNGEN
Title (fr)
PROCEDE DE PRODUCTION DE 4-ARYLPIPERIDINE-3-CARBINOLS ET COMPOSES CORRESPONDANTS
Publication
Application
Priority
- IB 9901762 W 19991101
- US 10667398 P 19981102
Abstract (en)
[origin: WO0026187A1] Aryl-2-piperidones of formula (7) can be reduced to form aryl-piperidine carbinols of formula (1), which are useful in forming a variety of pharmaceutical compounds including paroxetine, in good yield and purity. Related compounds and synthesis schemes are also set forth. In said formulas, X represents a hydrogen atom, a halogen atom, a lower alkyl group, an aralkyl group, an alkoxy group, a dialkylamino group or an alkylthio group; R represents a hydrogen atom, a lower alkyl group, an aryl group, an aralkyl group, an alkoxycarbonyl group, aralkoxycarbonyl group or an aryloxycarbonyl group; and R<1> represents a hydrogen atom, a lower alkyl group, an aryl group or an aralkyl group.
IPC 1-7
IPC 8 full level
C07D 211/22 (2006.01); C07D 211/76 (2006.01)
CPC (source: EP)
C07D 211/22 (2013.01); C07D 211/76 (2013.01)
Citation (search report)
See references of WO 0026187A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0026187 A1 20000511; AU 6360999 A 20000522; CZ 20011465 A3 20010815; EP 1124802 A1 20010822; NO 20012099 D0 20010427; NO 20012099 L 20010702
DOCDB simple family (application)
IB 9901762 W 19991101; AU 6360999 A 19991101; CZ 20011465 A 19991101; EP 99951035 A 19991101; NO 20012099 A 20010427