EP 1125131 A1 20010822 - SCREENING TEST FOR EARLY DETECTION OF COLORECTAL CANCER
Title (en)
SCREENING TEST FOR EARLY DETECTION OF COLORECTAL CANCER
Title (de)
SCREENINGTEST ZUM FRÜHNACHWEIS VON DARMKREBS
Title (fr)
TEST DE DEPISTAGE PERMETTANT UN DEPISTAGE PRECOCE DU CANCER COLORECTAL
Publication
Application
Priority
- CA 9901034 W 19991103
- CA 2253093 A 19981106
- US 27010399 A 19990316
Abstract (en)
[origin: WO0028329A1] A method for detecting neoplasia or cancer of the colon or rectum comprising obtaining a sample of colorectal mucus from the rectum of a patient, and detecting the presence of a marker selected from the group consisting of long chain aliphatic aldehydes containing 12 - 20 carbon atoms, particularly CH3(CH2)14CHO and CH3(CH2)16CHO; and plasmalogen-bound precursors thereof. Preferably the method comprises treating the sample with Schiff's Reagent and detecting neoplasia or cancer of the colon or rectum based upon the coloration produced at about 550 - 590 nm in the sample by the treatment. The method does not require the step of adding an enzyme for detecting the disaccharide marker beta -D-Gal(1-3)-D-GalNAc( alpha 1-Thr/Ser) and a saccharide marker containing D-galactose and/or 2-acetamido-2-deoxy-D-galactose.
IPC 1-7
IPC 8 full level
G01N 21/77 (2006.01); G01N 21/78 (2006.01); G01N 33/574 (2006.01); G01N 33/92 (2006.01)
CPC (source: EP)
G01N 33/57419 (2013.01); G01N 33/57446 (2013.01); G01N 33/57484 (2013.01)
Citation (search report)
See references of WO 0028329A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0028329 A1 20000518; AU 1022700 A 20000529; AU 766057 B2 20031009; BR 9915005 A 20011120; EP 1125131 A1 20010822; IL 139545 A0 20020210; JP 2002529739 A 20020910
DOCDB simple family (application)
CA 9901034 W 19991103; AU 1022700 A 19991103; BR 9915005 A 19991103; EP 99953473 A 19991103; IL 13954599 A 19991103; JP 2000581456 A 19991103