EP 1127116 A2 20010829 - ANTIGEN-BINDING PROTEINS COMPRISING A LINKER WHICH CONFERS RESTRICTED CONFORMATIONAL FLEXIBILITY
Title (en)
ANTIGEN-BINDING PROTEINS COMPRISING A LINKER WHICH CONFERS RESTRICTED CONFORMATIONAL FLEXIBILITY
Title (de)
ANTIGENBINDUNGSPROTEINE MIT EINER KOPPLUNG, DIE DIE STRUKTURELLE BEWEGLICHKEIT EINSCHRÄNKT
Title (fr)
PROTEINES DE FIXATION D'ANTIGENE
Publication
Application
Priority
- EP 99957977 A 19991022
- EP 9908323 W 19991022
- EP 9806991 W 19981027
- EP 99303118 A 19990422
Abstract (en)
[origin: WO0024884A2] Use of a polypeptide linker group, the amino acid sequence of which group confers restricted conformational flexibility, as a linking group to link binding units, preferably antigen binding units comprising heavy chain variable domains derived from an immunoglobulin naturally devoid of light chains, in a multivalent binding protein.
IPC 1-7
IPC 8 full level
C07K 7/06 (2006.01); C07K 16/26 (2006.01); C07K 16/44 (2006.01); C07K 16/46 (2006.01); C07K 19/00 (2006.01); C12N 1/19 (2006.01); C12N 15/11 (2006.01); C12N 15/62 (2006.01); C12N 15/81 (2006.01)
CPC (source: EP)
C07K 7/06 (2013.01); C07K 16/26 (2013.01); C07K 16/44 (2013.01); C07K 19/00 (2013.01); C12N 15/62 (2013.01); C07K 2317/22 (2013.01); C07K 2317/31 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 0024884A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0024884 A2 20000504; WO 0024884 A3 20000803; AU 1550300 A 20000515; BR 9914829 A 20010710; CA 2348839 A1 20000504; EP 1002861 A1 20000524; EP 1127116 A2 20010829
DOCDB simple family (application)
EP 9908323 W 19991022; AU 1550300 A 19991022; BR 9914829 A 19991022; CA 2348839 A 19991022; EP 99303118 A 19990422; EP 99957977 A 19991022