EP 1131280 B1 20040811 - PREPARATION OF 5-AMINO-ISOPHTHALAMIDES
Title (en)
PREPARATION OF 5-AMINO-ISOPHTHALAMIDES
Title (de)
HERSTELLUNG VON 5-AMINO-ISOPHTHALAMIDEN
Title (fr)
PREPARATION DE 5-AMINO-ISOPHTHALAMIDES
Publication
Application
Priority
- GB 9903795 W 19991115
- GB 9825095 A 19981116
Abstract (en)
[origin: WO0029372A1] A process for preparing 5-amino-N,N'-bis(R)isophthalamides, where A is 2,3-dihydroxypropyl or 1,3-dihydroxyisopropyl, useful as intermediates in preparing iodinated diagnostic agents, which comprises reacting a di-lower-alkyl 5-nitroisophthalate with a compound of the formula RNH2 in the presence of a basic catalyst and without isolating the intermediate 5-nitro-N,N'-bis(R)isophthalamide, catalytically hydrogenating the latter.
IPC 1-7
IPC 8 full level
C07C 231/12 (2006.01); A61K 49/04 (2006.01); C07B 61/00 (2006.01); C07C 231/08 (2006.01); C07C 237/32 (2006.01)
CPC (source: EP US)
C07C 231/08 (2013.01 - EP US)
C-Set (source: EP US)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0029372 A1 20000525; AT E273271 T1 20040815; AU 1066600 A 20000605; DE 69919382 D1 20040916; DE 69919382 T2 20051006; EP 1131280 A1 20010912; EP 1131280 B1 20040811; ES 2226455 T3 20050316; GB 9825095 D0 19990113; JP 2002529530 A 20020910; JP 4721518 B2 20110713; NO 20012325 D0 20010511; NO 20012325 L 20010511; NO 328678 B1 20100426; US 2002095053 A1 20020718; US 6441235 B1 20020827
DOCDB simple family (application)
GB 9903795 W 19991115; AT 99954254 T 19991115; AU 1066600 A 19991115; DE 69919382 T 19991115; EP 99954254 A 19991115; ES 99954254 T 19991115; GB 9825095 A 19981116; JP 2000582360 A 19991115; NO 20012325 A 20010511; US 85512401 A 20010514