EP 1131354 A1 20010912 - CONTRACEPTIVE ANTIBODY VACCINES
Title (en)
CONTRACEPTIVE ANTIBODY VACCINES
Title (de)
IMPFSTOFFE ZUR EMPFÄNGNISVERHÜTUNG BASIEREND AUF ANTIKÖRPERN
Title (fr)
VACCINS CONTRACEPTIFS CONTENANT UN ANTICORPS
Publication
Application
Priority
- US 9926671 W 19991112
- US 10832598 P 19981113
Abstract (en)
[origin: WO0029443A1] The invention provides an antibody contraceptive vaccine comprising an antibody that has at least one CDR containing a portion of an antigen of a cell or protein associated with reproductive function and which antibody has an enhanced ability to elicit an anti-idiotype response, for example, by substituting one or more variable region cysteine residues that form intrachain disulfide bonds with an amino acid residue that does not have a sulfhydryl group, such that the intrachain disulfide bond does not form. The invention further provides methods of contraception using the antibody contraceptive vaccines of the invention.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 15/18 (2006.01); C07K 16/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
A61P 15/18 (2017.12); C07K 16/00 (2013.01); A61K 2039/505 (2013.01); C07K 2318/10 (2013.01); C07K 2319/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 0029443 A1 20000525; WO 0029443 A9 20010322; AU 1719000 A 20000605; AU 753753 B2 20021024; CA 2350917 A1 20000525; EP 1131354 A1 20010912; EP 1131354 A4 20030102; IL 143100 A0 20020421; JP 2003535021 A 20031125; MX PA01004778 A 20030721
DOCDB simple family (application)
US 9926671 W 19991112; AU 1719000 A 19991112; CA 2350917 A 19991112; EP 99960285 A 19991112; IL 14310099 A 19991112; JP 2000582428 A 19991112; MX PA01004778 A 19991112